8FJV
Human GAR transformylase in complex with GAR substrate and AGF362 inhibitor
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Trifunctional purine biosynthetic protein adenosine-3 | polymer | 210 | 22810.1 | 1 | UniProt (P22102) Pfam (PF00551) In PDB | Homo sapiens (human) | |
2 | A | GLYCINAMIDE RIBONUCLEOTIDE | non-polymer | 284.2 | 1 | Chemie (GAR) | |||
3 | A | N-{4-[4-(2-amino-4-oxo-3,4-dihydro-5H-pyrrolo[3,2-d]pyrimidin-5-yl)butyl]-3-fluorothiophene-2-carbonyl}-L-glutamic acid | non-polymer | 479.5 | 1 | Chemie (Y72) | |||
4 | water | water | 18.0 | 40 | Chemie (HOH) |
Sequence modifications
A: 808 - 1010 (UniProt: P22102)
PDB | External Database | Details |
---|---|---|
Met 807 | - | initiating methionine |
His 1011 | - | expression tag |
His 1012 | - | expression tag |
His 1013 | - | expression tag |
His 1014 | - | expression tag |
His 1015 | - | expression tag |
His 1016 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 22810.1 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 763.6 | |
All* | Total formula weight | 23573.8 |