8FJI
Crystal structure of RalA in a covalent complex with SOF-367
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (B) | Ras-related protein Ral-A | polymer | 186 | 21303.8 | 1 | UniProt (P11233) Pfam (PF00071) | Homo sapiens (human) | RalA GTPase |
| 2 | B (B) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) PubChem (136073927) PubChem (135398619) PubChem (135402030) PubChem (135431654) PubChem (135566337) PubChem (135760556) PubChem (136026707) PubChem (136053418) PubChem (136663964) PubChem (136664748) PubChem (136759848) PubChem (136759849) PubChem (136759850) PubChem (136836636) PubChem (136847074) PubChem (172898537) | |||
| 3 | C (B) | 8-[fluoro(dihydroxy)-lambda~4~-sulfanyl]-N-(2-methoxypyridin-3-yl)-2,3-dihydro-1,4-benzodioxine-5-sulfonamide | non-polymer | 404.4 | 1 | Chemie (Y0M) PubChem (156513160) | |||
| 4 | D, E, F (B) | CALCIUM ION | non-polymer | 40.1 | 3 | Chemie (CA) PubChem (271) | |||
| 5 | G (B) | water | water | 18.0 | 195 | Chemie (HOH) |
Sequence modifications
B: 1 - 178 (UniProt: P11233)
| PDB | External Database | Details |
|---|---|---|
| Leu 179 | - | expression tag |
| Glu 180 | - | expression tag |
| His 181 | - | expression tag |
| His 182 | - | expression tag |
| His 183 | - | expression tag |
| His 184 | - | expression tag |
| His 185 | - | expression tag |
| His 186 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 21303.8 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 967.8 | |
| All* | Total formula weight | 22271.7 |
