8FJH
Crystal structure of RalA in a covalent complex with SOF-531
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (B) | Ras-related protein Ral-A | polymer | 186 | 21303.8 | 1 | UniProt (P11233) Pfam (PF00071) | Homo sapiens (human) | RalA GTPase |
| 2 | B (B) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) | |||
| 3 | C (B) | 8-[bis(oxidanyl)-$l^{3}-sulfanyl]-~{N}-(3-fluoranyl-5-methoxy-phenyl)-2,3-dihydro-1,4-benzodioxine-5-sulfonamide | non-polymer | 421.4 | 1 | Chemie (Y0P) | |||
| 4 | D, E, F (B) | CALCIUM ION | non-polymer | 40.1 | 3 | Chemie (CA) | |||
| 5 | G (B) | water | water | 18.0 | 244 | Chemie (HOH) |
Sequence modifications
B: 1 - 178 (UniProt: P11233)
| PDB | External Database | Details |
|---|---|---|
| Leu 179 | - | expression tag |
| Glu 180 | - | expression tag |
| His 181 | - | expression tag |
| His 182 | - | expression tag |
| His 183 | - | expression tag |
| His 184 | - | expression tag |
| His 185 | - | expression tag |
| His 186 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 21303.8 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 984.8 | |
| All* | Total formula weight | 22288.7 |
