8FJ0
Crystal Structure of the Tick Evasin EVA-AAM1001(Y44A) Complexed to Human Chemokine CCL2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Evasin P1243 | polymer | 103 | 11210.5 | 3 | UniProt (A0A0C9S461) Pfam (PF19429) | Amblyomma americanum (Lone Star tick) | |
| 2 | D, E, F (D, F, E) | C-C motif chemokine 2 | polymer | 76 | 8673.0 | 3 | UniProt (P13500) Pfam (PF00048) | Homo sapiens (human) | HC11,Monocyte chemoattractant protein 1,Monocyte chemotactic and activating factor,MCAF,Monocyte chemotactic protein 1,MCP-1,Monocyte secretory protein JE,Small-inducible cytokine A2 |
| 3 | G, H, I, J, K (A, B, C, D, E) | water | water | 18.0 | 11 | Chemie (HOH) |
Sequence modifications
A, B, C: 1 - 103 (UniProt: A0A0C9S461)
D, F, E: 1 - 76 (UniProt: P13500)
| PDB | External Database | Details |
|---|---|---|
| Ala 46 | Tyr 66 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Ala 8 | Pro 31 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 59650.7 | |
| All* | Total formula weight | 59650.7 |
