8FHY
Crystal structure of the SARS-CoV-2 receptor binding domain in complex with neutralizing antibody WRAIR-5021
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D, G (I, A, D) | Spike protein S1 | polymer | 205 | 23073.8 | 3 | UniProt (P0DTC2) Pfam (PF09408) | Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2 2019-nCoV COVID-19 virus) | |
| 2 | B, E, H (L, B, E) | WRAIR-5021 Fab Light chain | polymer | 214 | 23356.9 | 3 | Macaca mulatta | ||
| 3 | C, F, I (H, C, F) | WRAIR-5021 Fab Heavy chain | polymer | 220 | 23483.3 | 3 | Macaca mulatta | ||
| 4 | AA, BA, DA, EA, FA... (D, E, F, I, L...) | GLYCEROL | non-polymer | 92.1 | 21 | Chemie (GOL) | |||
| 5 | CA, L, T (D, I, A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) | |||
| 6 | Y (D) | MALONATE ION | non-polymer | 102.0 | 1 | Chemie (MLI) | |||
| 7 | IA, JA, KA, LA, MA... (I, L, H, A, B...) | water | water | 18.0 | 483 | Chemie (HOH) |
Sequence modifications
I, A, D: 331 - 527 (UniProt: P0DTC2)
| PDB | External Database | Details |
|---|---|---|
| Gly 528 | - | expression tag |
| Ser 529 | - | expression tag |
| His 530 | - | expression tag |
| His 531 | - | expression tag |
| His 532 | - | expression tag |
| His 533 | - | expression tag |
| His 534 | - | expression tag |
| His 535 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 9 |
| Total formula weight | 209741.9 | |
| Non-Polymers* | Number of molecules | 25 |
| Total formula weight | 2699.6 | |
| All* | Total formula weight | 212441.6 |
