8FHY

Crystal structure of the SARS-CoV-2 receptor binding domain in complex with neutralizing antibody WRAIR-5021

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	I, A, D	Spike protein S1	polymer	205	23073.8	3	UniProt (P0DTC2) Pfam (PF09408) In PDB	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2 2019-nCoV COVID-19 virus)
2	L, B, E	WRAIR-5021 Fab Light chain	polymer	214	23356.9	3		Macaca mulatta
3	H, C, F	WRAIR-5021 Fab Heavy chain	polymer	220	23483.3	3		Macaca mulatta
4	D, E, F, I, L...	GLYCEROL	non-polymer		92.1	21	Chemie (GOL)
5	D, I, A	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	3	Chemie (NAG)
6	D	MALONATE ION	non-polymer		102.0	1	Chemie (MLI)
7		water	water		18.0	483	Chemie (HOH)

Sequence modifications

I, A, D: 331 - 527 (UniProt: P0DTC2)

PDB	External Database	Details
Gly 528	-	expression tag
Ser 529	-	expression tag
His 530	-	expression tag
His 531	-	expression tag
His 532	-	expression tag
His 533	-	expression tag
His 534	-	expression tag
His 535	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	9
	Total formula weight	209741.9
Non-Polymers*	Number of molecules	25
	Total formula weight	2699.6
All*	Total formula weight	212441.6

*Water molecules are not included.