8FHI
Wildtype rabbit TRPV5 in nanodiscs in complex with oleoyl coenzyme A, Open stated
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Transient receptor potential cation channel subfamily V member 5 | polymer | 739 | 83784.6 | 4 | UniProt (Q9XSM3) Pfam (PF12796) Pfam (PF00023) Pfam (PF00520) | Oryctolagus cuniculus (rabbit) | TrpV5,Epithelial calcium channel 1,ECaC1,Osm-9-like TRP channel 3,OTRPC3 |
| 2 | E, F, I, J, M... (A, B, C, D) | ERGOSTEROL | non-polymer | 396.6 | 8 | Chemie (ERG) | |||
| 3 | G, K, O, T (A, B, C, D) | S-{(3R,5R,9R)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9-trihydroxy-8,8-dimethyl-3,5-dioxido-10,14-dioxo-2,4,6-trioxa-11,15-diaza-3lambda~5~,5lambda~5~-diphosphaheptadecan-17-yl} (9Z)-octadec-9-enethioate (non-preferred name) | non-polymer | 1032.0 | 4 | Chemie (3VV) | |||
| 4 | H, L, P, Q (A, B, C, D) | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate | non-polymer | 760.1 | 4 | Chemie (POV) |
Sequence modifications
A, B, C, D: 1 - 730 (UniProt: Q9XSM3)
| PDB | External Database | Details |
|---|---|---|
| Thr 731 | - | expression tag |
| Glu 732 | - | expression tag |
| Thr 733 | - | expression tag |
| Ser 734 | - | expression tag |
| Gln 735 | - | expression tag |
| Val 736 | - | expression tag |
| Ala 737 | - | expression tag |
| Pro 738 | - | expression tag |
| Ala 739 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 335138.3 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 10341.4 | |
| All* | Total formula weight | 345479.8 |
