8FE7
Crystal structure of human O-GlcNAc transferase (OGT) in complex with an exosite-binding peptide (SMG9) and UDP-GlcNAc
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G (A, C, E, G) | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | polymer | 723 | 80974.5 | 4 | UniProt (O15294) Pfam (PF13424) Pfam (PF13414) Pfam (PF13844) | Homo sapiens (human) | O-GlcNAc transferase subunit p110,O-linked N-acetylglucosamine transferase 110 kDa subunit,OGT |
| 2 | B, D, F, H (B, D, F, H) | Nonsense-mediated mRNA decay factor SMG9 | polymer | 12 | 1472.6 | 4 | UniProt (Q9H0W8) | Homo sapiens | |
| 3 | I, J, K, L (A, C, E, G) | URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE | non-polymer | 607.4 | 4 | Chemie (UD1) |
Sequence modifications
A, C, E, G: 313 - 1031 (UniProt: O15294)
| PDB | External Database | Details |
|---|---|---|
| Gly 309 | - | expression tag |
| Pro 310 | - | expression tag |
| Gly 311 | - | expression tag |
| Ser 312 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 329788.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 2429.4 | |
| All* | Total formula weight | 332217.9 |
