8FE7
Crystal structure of human O-GlcNAc transferase (OGT) in complex with an exosite-binding peptide (SMG9) and UDP-GlcNAc
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | ACT_SITE: Proton acceptor => ECO:0000305|PubMed:21240259, ECO:0000305|PubMed:26678539 |
| Chain | Residue | Details |
| A | GLY508 | |
| C | GLY508 | |
| E | GLY508 | |
| G | GLY508 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 24 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:23103939, ECO:0007744|PDB:4GYW |
| Chain | Residue | Details |
| A | GLN849 | |
| C | CYS911 | |
| C | GLY930 | |
| C | THR935 | |
| E | GLN849 | |
| E | ALA852 | |
| E | GLN906 | |
| E | CYS911 | |
| E | GLY930 | |
| E | THR935 | |
| G | GLN849 | |
| A | ALA852 | |
| G | ALA852 | |
| G | GLN906 | |
| G | CYS911 | |
| G | GLY930 | |
| G | THR935 | |
| A | GLN906 | |
| A | CYS911 | |
| A | GLY930 | |
| A | THR935 | |
| C | GLN849 | |
| C | ALA852 | |
| C | GLN906 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphothreonine; by AMPK => ECO:0000269|PubMed:24563466, ECO:0000269|PubMed:37541260 |
| Chain | Residue | Details |
| A | ASP454 | |
| C | ASP454 | |
| E | ASP454 | |
| G | ASP454 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphotyrosine => ECO:0000250|UniProtKB:P56558 |
| Chain | Residue | Details |
| A | LYS989 | |
| C | LYS989 | |
| E | LYS989 | |
| G | LYS989 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | CARBOHYD: O-linked (GlcNAc) serine; by autocatalysis => ECO:0000269|PubMed:27713473 |
| Chain | Residue | Details |
| A | GLN399 | |
| C | GLN399 | |
| E | GLN399 | |
| G | GLN399 |
