8FDW
Cryo-EM structure of SARS-CoV-2 postfusion spike in membrane
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (B, A, C) | Spike protein S2 | polymer | 625 | 68176.2 | 3 | UniProt (P0DTC2) Pfam (PF01601) | Severe acute respiratory syndrome coronavirus | |
| 2 | D, E, I, J, N... (D, E, I, J, N...) | alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 6 | In PDB GlyTouCan (G48068RF) | |||
| 3 | F, K, P (F, K, P) | alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 3 | In PDB GlyTouCan (G62182OO) | |||
| 4 | G, H, L, M, Q... (G, H, L, M, Q...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 6 | In PDB GlyTouCan (G42666HT) | |||
| 5 | AA, S, W (C, B, A) | alpha-D-mannopyranose | non-polymer | 180.2 | 3 | Chemie (MAN) | |||
| 6 | BA, CA, DA, T, U... (C, B, A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 9 | Chemie (NAG) |
Sequence modifications
B, A, C: 686 - 1273 (UniProt: P0DTC2)
| PDB | External Database | Details |
|---|---|---|
| Leu 1274 | - | expression tag |
| Glu 1275 | - | expression tag |
| Ser 1276 | - | expression tag |
| Gly 1277 | - | expression tag |
| Gly 1278 | - | expression tag |
| Gly 1279 | - | expression tag |
| Ser 1280 | - | expression tag |
| Ala 1281 | - | expression tag |
| Trp 1282 | - | expression tag |
| Ser 1283 | - | expression tag |
| His 1284 | - | expression tag |
| Pro 1285 | - | expression tag |
| Gln 1286 | - | expression tag |
| Phe 1287 | - | expression tag |
| Glu 1288 | - | expression tag |
| Lys 1289 | - | expression tag |
| Gly 1290 | - | expression tag |
| Gly 1291 | - | expression tag |
| Gly 1292 | - | expression tag |
| Ser 1293 | - | expression tag |
| Gly 1294 | - | expression tag |
| Gly 1295 | - | expression tag |
| Gly 1296 | - | expression tag |
| Ser 1297 | - | expression tag |
| Gly 1298 | - | expression tag |
| Gly 1299 | - | expression tag |
| Ser 1300 | - | expression tag |
| Ser 1301 | - | expression tag |
| Ala 1302 | - | expression tag |
| Trp 1303 | - | expression tag |
| Ser 1304 | - | expression tag |
| His 1305 | - | expression tag |
| Pro 1306 | - | expression tag |
| Gln 1307 | - | expression tag |
| Phe 1308 | - | expression tag |
| Glu 1309 | - | expression tag |
| Lys 1310 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 204528.6 | |
| Branched | Number of molecules | 15 |
| Total formula weight | 8798.1 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 2531.3 | |
| All* | Total formula weight | 215858.0 |
