8FDW
Cryo-EM structure of SARS-CoV-2 postfusion spike in membrane
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016020 | cellular_component | membrane |
| A | 0019031 | cellular_component | viral envelope |
| A | 0019064 | biological_process | fusion of virus membrane with host plasma membrane |
| A | 0039654 | biological_process | fusion of virus membrane with host endosome membrane |
| A | 0046813 | biological_process | receptor-mediated virion attachment to host cell |
| A | 0055036 | cellular_component | virion membrane |
| A | 0075509 | biological_process | endocytosis involved in viral entry into host cell |
| B | 0016020 | cellular_component | membrane |
| B | 0019031 | cellular_component | viral envelope |
| B | 0019064 | biological_process | fusion of virus membrane with host plasma membrane |
| B | 0039654 | biological_process | fusion of virus membrane with host endosome membrane |
| B | 0046813 | biological_process | receptor-mediated virion attachment to host cell |
| B | 0055036 | cellular_component | virion membrane |
| B | 0075509 | biological_process | endocytosis involved in viral entry into host cell |
| C | 0016020 | cellular_component | membrane |
| C | 0019031 | cellular_component | viral envelope |
| C | 0019064 | biological_process | fusion of virus membrane with host plasma membrane |
| C | 0039654 | biological_process | fusion of virus membrane with host endosome membrane |
| C | 0046813 | biological_process | receptor-mediated virion attachment to host cell |
| C | 0055036 | cellular_component | virion membrane |
| C | 0075509 | biological_process | endocytosis involved in viral entry into host cell |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 60 |
| Details | TRANSMEM: Helical => ECO:0000255|HAMAP-Rule:MF_04099 |
| Chain | Residue | Details |
| B | TRP1214-LEU1234 | |
| A | TRP1214-LEU1234 | |
| C | TRP1214-LEU1234 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 114 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000255|HAMAP-Rule:MF_04099 |
| Chain | Residue | Details |
| B | CYS1235-THR1273 | |
| A | CYS1235-THR1273 | |
| C | CYS1235-THR1273 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | SITE: Cleavage; by host TMPRSS2 or CTSL => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32703818, ECO:0000269|PubMed:34159616 |
| Chain | Residue | Details |
| B | ARG815 | |
| A | ARG815 | |
| C | ARG815 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 15 |
| Details | LIPID: S-palmitoyl cysteine; by host ZDHHC20 => ECO:0000269|PubMed:34599882 |
| Chain | Residue | Details |
| B | CYS1235 | |
| A | CYS1243 | |
| C | CYS1235 | |
| C | CYS1236 | |
| C | CYS1240 | |
| C | CYS1241 | |
| C | CYS1243 | |
| B | CYS1236 | |
| B | CYS1240 | |
| B | CYS1241 | |
| B | CYS1243 | |
| A | CYS1235 | |
| A | CYS1236 | |
| A | CYS1240 | |
| A | CYS1241 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 15 |
| Details | LIPID: S-palmitoyl cysteine; by host ZDHHC20; partial => ECO:0000269|PubMed:34599882 |
| Chain | Residue | Details |
| B | CYS1247 | |
| A | CYS1254 | |
| C | CYS1247 | |
| C | CYS1248 | |
| C | CYS1250 | |
| C | CYS1253 | |
| C | CYS1254 | |
| B | CYS1248 | |
| B | CYS1250 | |
| B | CYS1253 | |
| B | CYS1254 | |
| A | CYS1247 | |
| A | CYS1248 | |
| A | CYS1250 | |
| A | CYS1253 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 3 |
| Details | CARBOHYD: N-linked (GlcNAc...) (high mannose) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32155444, ECO:0000269|PubMed:32363391, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
| Chain | Residue | Details |
| B | ASN709 | |
| A | ASN709 | |
| C | ASN709 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 9 |
| Details | CARBOHYD: N-linked (GlcNAc...) (hybrid) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32155444, ECO:0000269|PubMed:32363391, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
| Chain | Residue | Details |
| B | ASN717 | |
| B | ASN801 | |
| B | ASN1074 | |
| A | ASN717 | |
| A | ASN801 | |
| A | ASN1074 | |
| C | ASN717 | |
| C | ASN801 | |
| C | ASN1074 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 3 |
| Details | CARBOHYD: N-linked (GlcNAc...) (complex) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32155444, ECO:0000269|PubMed:32363391, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
| Chain | Residue | Details |
| B | ASN1098 | |
| A | ASN1098 | |
| C | ASN1098 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 3 |
| Details | CARBOHYD: N-linked (GlcNAc...) (complex) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32155444, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
| Chain | Residue | Details |
| B | ASN1134 | |
| A | ASN1134 | |
| C | ASN1134 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 6 |
| Details | CARBOHYD: N-linked (GlcNAc...) (complex) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
| Chain | Residue | Details |
| B | ASN1158 | |
| B | ASN1173 | |
| A | ASN1158 | |
| A | ASN1173 | |
| C | ASN1158 | |
| C | ASN1173 |
| site_id | SWS_FT_FI11 |
| Number of Residues | 3 |
| Details | CARBOHYD: N-linked (GlcNAc...) (complex) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32363391, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
| Chain | Residue | Details |
| B | ASN1194 | |
| A | ASN1194 | |
| C | ASN1194 |
