8FCY

Engineered human dynein motor domain in microtubule-bound state

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Cytoplasmic dynein 1 heavy chain 1,Serine--tRNA ligase	polymer	3130	357931.6	1	UniProt (Q14204) UniProt (Q5SJX7) Pfam (PF08393) Pfam (PF03028) Pfam (PF18198) Pfam (PF18199) Pfam (PF12774) Pfam (PF17852) Pfam (PF12775) Pfam (PF22597) Pfam (PF12780) Pfam (PF12777) Pfam (PF02403) Pfam (PF12781)	Homo sapiens (human)
2	B, D, E (A)	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	3	Chemie (ADP)
3	C (A)	ADENOSINE-5'-TRIPHOSPHATE	non-polymer		507.2	1	Chemie (ATP)

Sequence modifications

A: 3 - 1826 (UniProt: Q14204)

PDB	External Database	Details
Gly 1	-	expression tag
Ser 2	-	expression tag

A: 1827 - 1893 (UniProt: Q5SJX7)
A: 1894 - 3128 (UniProt: Q14204)

PDB	External Database	Details
Glu 3129	-	expression tag
Phe 3130	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	357931.6
Non-Polymers*	Number of molecules	4
	Total formula weight	1788.8
All*	Total formula weight	359720.4

*Water molecules are not included.