8FBH
Crystal structure of NSD1 Mutant-T1927A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Histone-lysine N-methyltransferase, H3 lysine-36 specific | polymer | 232 | 26466.2 | 1 | UniProt (O88491) Pfam (PF17907) Pfam (PF00856) In PDB | Mus musculus (house mouse) | H3-K36-HMTase,Nuclear receptor-binding SET domain-containing protein 1,NR-binding SET domain-containing protein |
| 2 | A | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) | |||
| 3 | A | S-ADENOSYLMETHIONINE | non-polymer | 398.4 | 1 | Chemie (SAM) | |||
| 4 | A | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 5 | A | UNKNOWN ATOM OR ION | non-polymer | 3 | Chemie (UNX) | ||||
| 6 | water | water | 18.0 | 60 | Chemie (HOH) |
Sequence modifications
A: 1750 - 1980 (UniProt: O88491)
| PDB | External Database | Details |
|---|---|---|
| Gly 1749 | - | expression tag |
| Gly 1827 | Val 1827 | conflict |
| Glu 1841 | Asp 1841 | conflict |
| Ala 1927 | Thr 1927 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 26466.2 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 690.7 | |
| All* | Total formula weight | 27156.9 |
