8FAZ

Cryo-EM structure of the human BCDX2 complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (B)	DNA repair protein RAD51 homolog 2	polymer	356	39125.9	1	UniProt (O15315) Pfam (PF08423)	Homo sapiens (human)	R51H2,RAD51 homolog B,Rad51B,RAD51-like protein 1
2	B (C)	DNA repair protein RAD51 homolog 3	polymer	376	42244.6	1	UniProt (O43502) Pfam (PF08423)	Homo sapiens (human)	R51H3,RAD51 homolog C,RAD51-like protein 2
3	C (D)	DNA repair protein RAD51 homolog 4	polymer	328	35084.3	1	UniProt (O75771) Pfam (PF21794) Pfam (PF08423)	Homo sapiens (human)	R51H3,RAD51 homolog D,RAD51-like protein 3,TRAD
4	D (X)	DNA repair protein XRCC2	polymer	288	32992.5	1	UniProt (O43543) Pfam (PF08423)	Homo sapiens (human)	X-ray repair cross-complementing protein 2
5	E (C)	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	1	Chemie (ADP)
6	F, H (D, X)	PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER	non-polymer		506.2	2	Chemie (ANP)
7	G, I (D, X)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)

Sequence modifications

B: 1 - 350 (UniProt: O15315)

PDB	External Database	Details
His 351	-	expression tag
His 352	-	expression tag
His 353	-	expression tag
His 354	-	expression tag
His 355	-	expression tag
His 356	-	expression tag

X: 1 - 280 (UniProt: O43543)

PDB	External Database	Details
Asp 281	-	expression tag
Tyr 282	-	expression tag
Lys 283	-	expression tag
Asp 284	-	expression tag
Asp 285	-	expression tag
Asp 286	-	expression tag
Asp 287	-	expression tag
Lys 288	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	149447.2
Non-Polymers*	Number of molecules	5
	Total formula weight	1488.2
All*	Total formula weight	150935.4

*Water molecules are not included.