8FAZ

Cryo-EM structure of the human BCDX2 complex

Functional Information from GO Data

Chain	GOid	namespace	contents
B	0000166	molecular_function	nucleotide binding
B	0000400	molecular_function	four-way junction DNA binding
B	0000724	biological_process	double-strand break repair via homologous recombination
B	0003677	molecular_function	DNA binding
B	0003690	molecular_function	double-stranded DNA binding
B	0003697	molecular_function	single-stranded DNA binding
B	0005515	molecular_function	protein binding
B	0005524	molecular_function	ATP binding
B	0005634	cellular_component	nucleus
B	0005654	cellular_component	nucleoplasm
B	0005657	cellular_component	replication fork
B	0006281	biological_process	DNA repair
B	0006310	biological_process	DNA recombination
B	0006974	biological_process	DNA damage response
B	0007131	biological_process	reciprocal meiotic recombination
B	0008094	molecular_function	ATP-dependent activity, acting on DNA
B	0010971	biological_process	positive regulation of G2/M transition of mitotic cell cycle
B	0033063	cellular_component	Rad51B-Rad51C-Rad51D-XRCC2 complex
B	0097435	biological_process	supramolecular fiber organization
B	0140664	molecular_function	ATP-dependent DNA damage sensor activity
C	0000166	molecular_function	nucleotide binding
C	0000400	molecular_function	four-way junction DNA binding
C	0000707	biological_process	meiotic DNA recombinase assembly
C	0000722	biological_process	telomere maintenance via recombination
C	0000724	biological_process	double-strand break repair via homologous recombination
C	0003677	molecular_function	DNA binding
C	0005515	molecular_function	protein binding
C	0005524	molecular_function	ATP binding
C	0005634	cellular_component	nucleus
C	0005654	cellular_component	nucleoplasm
C	0005657	cellular_component	replication fork
C	0005737	cellular_component	cytoplasm
C	0005739	cellular_component	mitochondrion
C	0005829	cellular_component	cytosol
C	0006281	biological_process	DNA repair
C	0006310	biological_process	DNA recombination
C	0006974	biological_process	DNA damage response
C	0007062	biological_process	sister chromatid cohesion
C	0007131	biological_process	reciprocal meiotic recombination
C	0008821	molecular_function	crossover junction DNA endonuclease activity
C	0010971	biological_process	positive regulation of G2/M transition of mitotic cell cycle
C	0031297	biological_process	replication fork processing
C	0033063	cellular_component	Rad51B-Rad51C-Rad51D-XRCC2 complex
C	0033065	cellular_component	Rad51C-XRCC3 complex
C	0043596	cellular_component	nuclear replication fork
C	0048471	cellular_component	perinuclear region of cytoplasm
C	0097435	biological_process	supramolecular fiber organization
C	0140664	molecular_function	ATP-dependent DNA damage sensor activity
D	0000166	molecular_function	nucleotide binding
D	0000400	molecular_function	four-way junction DNA binding
D	0000722	biological_process	telomere maintenance via recombination
D	0000723	biological_process	telomere maintenance
D	0000724	biological_process	double-strand break repair via homologous recombination
D	0000781	cellular_component	chromosome, telomeric region
D	0003677	molecular_function	DNA binding
D	0003697	molecular_function	single-stranded DNA binding
D	0005515	molecular_function	protein binding
D	0005524	molecular_function	ATP binding
D	0005634	cellular_component	nucleus
D	0005654	cellular_component	nucleoplasm
D	0005657	cellular_component	replication fork
D	0005813	cellular_component	centrosome
D	0005815	cellular_component	microtubule organizing center
D	0006281	biological_process	DNA repair
D	0006310	biological_process	DNA recombination
D	0006974	biological_process	DNA damage response
D	0007131	biological_process	reciprocal meiotic recombination
D	0008094	molecular_function	ATP-dependent activity, acting on DNA
D	0033063	cellular_component	Rad51B-Rad51C-Rad51D-XRCC2 complex
D	0042148	biological_process	DNA strand invasion
D	0043015	molecular_function	gamma-tubulin binding
D	0097435	biological_process	supramolecular fiber organization
D	0140664	molecular_function	ATP-dependent DNA damage sensor activity
X	0000278	biological_process	mitotic cell cycle
X	0000400	molecular_function	four-way junction DNA binding
X	0000724	biological_process	double-strand break repair via homologous recombination
X	0003677	molecular_function	DNA binding
X	0005515	molecular_function	protein binding
X	0005524	molecular_function	ATP binding
X	0005634	cellular_component	nucleus
X	0005654	cellular_component	nucleoplasm
X	0005657	cellular_component	replication fork
X	0005813	cellular_component	centrosome
X	0006281	biological_process	DNA repair
X	0006310	biological_process	DNA recombination
X	0006974	biological_process	DNA damage response
X	0007098	biological_process	centrosome cycle
X	0033063	cellular_component	Rad51B-Rad51C-Rad51D-XRCC2 complex
X	0042148	biological_process	DNA strand invasion
X	0051321	biological_process	meiotic cell cycle
X	0097435	biological_process	supramolecular fiber organization
X	0140664	molecular_function	ATP-dependent DNA damage sensor activity

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	14
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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