8FA2

Cryo-EM structure of the SARS-CoV-2 Omicron HR1-42G complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C	Scaffolded Spike protein S2' HR1	polymer	257	28818.2	3	UniProt (B2J981) UniProt (P0DTC2) Pfam (PF00210) In PDB	Nostoc punctiforme PCC 73102
2	D, E, F	Spike protein S2' 42G	polymer	46	4992.5	3	UniProt (P0DTC2) In PDB	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2)

Sequence modifications

A, B, C: 742 - 915 (UniProt: B2J981)

PDB	External Database	Details
Met 732	-	initiating methionine
Ser 733	-	expression tag
His 734	-	expression tag
His 735	-	expression tag
His 736	-	expression tag
His 737	-	expression tag
His 738	-	expression tag
His 739	-	expression tag
Gly 740	-	expression tag
Ser 741	-	expression tag
Ala 916	-	linker

A, B, C: 917 - 988 (UniProt: P0DTC2)

PDB	External Database	Details
His 954	Gln 954	conflict
Lys 969	Asn 969	conflict
Phe 981	Leu 981	conflict

D, E, F: 1157 - 1202 (UniProt: P0DTC2)

PDB	External Database	Details
Gly 1167	-	insertion

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	101432.0
All*	Total formula weight	101432.0

*Water molecules are not included.