8F74
LRRC8A(T48D):C conformation 2 top focus
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E (A, B, C, D, E) | Volume-regulated anion channel subunit LRRC8A,Soluble cytochrome b562 | polymer | 911 | 105544.1 | 5 | UniProt (Q80WG5) UniProt (P0ABE7) Pfam (PF12534) Pfam (PF07361) Pfam (PF13855) | Mus musculus (house mouse) | Leucine-rich repeat-containing protein 8A,Protein ebouriffe,ebo,Cytochrome b-562 |
| 2 | F (F) | Volume-regulated anion channel subunit LRRC8C | polymer | 813 | 93624.6 | 1 | UniProt (Q8R502) Pfam (PF12534) Pfam (PF13855) | Mus musculus (house mouse) | Factor for adipocyte differentiation 158,Leucine-rich repeat-containing protein 8C |
| 3 | G, H, I, J, K... (A, B, C, D, E...) | 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine | non-polymer | 744.0 | 15 | Chemie (PEE) | |||
| 4 | AA, V, W, X, Y... (F, A, B, C, D...) | water | water | 18.0 | 6 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E: 1 - 68 (UniProt: Q80WG5)
A, B, C, D, E: 68 - 72 (UniProt: P0ABE7)
A, B, C, D, E: 92 - 810 (UniProt: Q80WG5)
F: 1 - 803 (UniProt: Q8R502)
| PDB | External Database | Details |
|---|---|---|
| Asp 48 | Thr 48 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Trp 68 | Met 29 | conflict |
| Ile 72 | His 124 | conflict |
| Leu 72 | - | linker |
| Asp 72 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Ser 811 | - | expression tag |
| Asn 812 | - | expression tag |
| Ser 813 | - | expression tag |
| Leu 814 | - | expression tag |
| Glu 815 | - | expression tag |
| Val 816 | - | expression tag |
| Leu 817 | - | expression tag |
| Phe 818 | - | expression tag |
| Gln 819 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ser 804 | - | expression tag |
| Asn 805 | - | expression tag |
| Ser 806 | - | expression tag |
| Glu 807 | - | expression tag |
| Asn 808 | - | expression tag |
| Leu 809 | - | expression tag |
| Tyr 810 | - | expression tag |
| Phe 811 | - | expression tag |
| Gln 812 | - | expression tag |
| Gly 813 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 621345.0 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 11160.5 | |
| All* | Total formula weight | 632505.5 |
