8F6B

Crystal structure of murine PolG2 hexamer bound to DNA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	PolG2	polymer	455	51200.1	6	UniProt (Q0VES3) Pfam (PF03129) UniProt (by SIFTS) (Q9QZM2)	Mus musculus (house mouse)
2	G, H, I, J (G, H, I, J)	DNA (5'-D(*CP*TP*GP*GP*TP*AP*GP*GP*CP*GP*CP*CP*TP*AP*CP*CP*AP*G)-3')	polymer	18	5517.6	4		Homo sapiens
3	K, W (A, B)	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
4	AA, BA, CA, DA, EA... (D, E, A, F, B...)	1,2-ETHANEDIOL	non-polymer		62.1	32	Chemie (EDO)
5	Q, V (A, B)	(4S)-2-METHYL-2,4-PENTANEDIOL	non-polymer		118.2	2	Chemie (MPD)
6	UA, VA (H, I)	SODIUM ION	non-polymer		23.0	2	Chemie (NA)
7	AB, BB, CB, DB, EB... (E, F, G, H, I...)	water	water		18.0	81	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F: 17 - 459 (UniProt: Q0VES3)

PDB	External Database	Details
Met 16	-	initiating methionine
Ala 460	-	expression tag
Ala 461	-	expression tag
Ala 462	-	expression tag
Leu 463	-	expression tag
Glu 464	-	expression tag
His 465	-	expression tag
His 466	-	expression tag
His 467	-	expression tag
His 468	-	expression tag
His 469	-	expression tag
His 470	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	10
	Total formula weight	329271.1
Non-Polymers*	Number of molecules	38
	Total formula weight	2452.7
All*	Total formula weight	331723.8

*Water molecules are not included.