8F5X
Crystal structure of human eosinophil-derived neurotoxin (EDN, ribonuclease 2) in complex with 5'-adenosine monophosphate (AMP)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Non-secretory ribonuclease | polymer | 135 | 15611.8 | 1 | UniProt (P10153) Pfam (PF00074) | Homo sapiens (human) | Eosinophil-derived neurotoxin,RNase UpI-2,Ribonuclease 2,RNase 2,Ribonuclease US |
| 2 | B, C, G (A) | SUCCINIC ACID | non-polymer | 118.1 | 3 | Chemie (SIN) | |||
| 3 | D, F, H, I (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 4 | E (A) | ADENOSINE MONOPHOSPHATE | non-polymer | 347.2 | 1 | Chemie (AMP) | |||
| 5 | J (A) | water | water | 18.0 | 111 | Chemie (HOH) |
Sequence modifications
A: 1 - 134 (UniProt: P10153)
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 15611.8 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 949.8 | |
| All* | Total formula weight | 16561.5 |
