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8F5U

Rabbit muscle pyruvate kinase in complex with magnesium, potassium and pyruvate

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
Pyruvate kinase PKMpolymer53158114.04UniProt (P11974)
Pfam (PF00224)
Pfam (PF02887)
Oryctolagus cuniculus (rabbit)Pyruvate kinase muscle isozyme,Threonine-protein kinase PKM2,Tyrosine-protein kinase PKM2
2DA, E, G, N, S...
(D, A, B, C)
GLYCEROLnon-polymer92.18Chemie (GOL)
3F, H
(A)
1,2-ETHANEDIOLnon-polymer62.12Chemie (EDO)
4AA, BA, I, J, O...
(D, A, B, C)
POTASSIUM IONnon-polymer39.18Chemie (K)
5CA, K, Q, W
(D, A, B, C)
MAGNESIUM IONnon-polymer24.34Chemie (MG)
6L, R
(A, B)
PYRUVIC ACIDnon-polymer88.12Chemie (PYR)
7M, X
(A, C)
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOLnon-polymer122.12Chemie (TRS)
8EA, FA, GA, HA
(A, B, C, D)
waterwater18.01051Chemie (HOH)
Sequence modifications
A, B, C, D: 0 - 530 (UniProt: P11974)
PDBExternal DatabaseDetails
Ala 400Ser 401variant
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight232456.1
Non-Polymers*Number of molecules26
Total formula weight1691.3
All*Total formula weight234147.4
*Water molecules are not included.

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PDB entries from 2025-10-08

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