8F59
LSD1-CoREST in complex with AW2 and SNAG peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Lysine-specific histone demethylase 1A | polymer | 871 | 95051.6 | 1 | UniProt (O60341) Pfam (PF04433) Pfam (PF01593) | Homo sapiens (human) | BRAF35-HDAC complex protein BHC110,Flavin-containing amine oxidase domain-containing protein 2,[histone H3]-dimethyl-L-lysine(4) FAD-dependent demethylase 1A |
| 2 | B (B) | REST corepressor 1 | polymer | 144 | 16459.7 | 1 | UniProt (Q9UKL0) Pfam (PF20878) Pfam (PF00249) | Homo sapiens (human) | Protein CoREST |
| 3 | C (C) | Zinc finger protein SNAI1 | polymer | 9 | 1102.4 | 1 | UniProt (O95863) | Homo sapiens | Protein snail homolog 1,Protein sna |
| 4 | D (A) | [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl (2R,3S,4S)-5-{5-[3-([1,1'-biphenyl]-4-yl)propanoyl]-7,8-dimethyl-2,4-dioxo-1,3,4,5-tetrahydrobenzo[g]pteridin-10(2H)-yl}-2,3,4-trihydroxypentyl dihydrogen diphosphate (non-preferred name) | non-polymer | 995.8 | 1 | Chemie (XB6) |
Sequence modifications
A: 1 - 852 (UniProt: O60341)
B: 305 - 440 (UniProt: Q9UKL0)
| PDB | External Database | Details |
|---|---|---|
| Gly -18 | - | expression tag |
| Ser -17 | - | expression tag |
| Ser -16 | - | expression tag |
| His -15 | - | expression tag |
| His -14 | - | expression tag |
| His -13 | - | expression tag |
| His -12 | - | expression tag |
| His -11 | - | expression tag |
| His -10 | - | expression tag |
| Ser -9 | - | expression tag |
| Ser -8 | - | expression tag |
| Gly -7 | - | expression tag |
| Leu -6 | - | expression tag |
| Val -5 | - | expression tag |
| Pro -4 | - | expression tag |
| Arg -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 297 | - | expression tag |
| Pro 298 | - | expression tag |
| Leu 299 | - | expression tag |
| Gly 300 | - | expression tag |
| Ser 301 | - | expression tag |
| Pro 302 | - | expression tag |
| Glu 303 | - | expression tag |
| Phe 304 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 112613.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 995.8 | |
| All* | Total formula weight | 113609.5 |
