8F0H
Structure of SARS-CoV-2 spike with antibody Fabs 2A10 and 1H2 (Local refinement of the RBD and Fabs 1H2 and 2A10)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | B | Antibody Fab 1H2 heavy chain | polymer | 124 | 13783.5 | 1 | Homo sapiens (Human) | ||
| 2 | C | Spike glycoprotein | polymer | 1212 | 134065.7 | 1 | UniProt (P0DTC2) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601) In PDB | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2) | S glycoprotein,E2,Peplomer protein |
| 3 | D | Antibody Fab 1H2 light chain | polymer | 101 | 10796.7 | 1 | Homo sapiens (Human) | ||
| 4 | H | Antibody Fab 2A10 heavy chain | polymer | 115 | 12750.3 | 1 | Homo sapiens (Human) | ||
| 5 | L | Antibody Fab 2A10 light chain | polymer | 109 | 11920.2 | 1 | Homo sapiens (Human) | ||
| 6 | M | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 1 | In PDB GlyTouCan (G21290RB) |
Sequence modifications
C: 14 - 1208 (UniProt: P0DTC2)
| PDB | External Database | Details |
|---|---|---|
| Met -3 | - | initiating methionine |
| Gly -2 | - | expression tag |
| Val -1 | - | expression tag |
| Lys 0 | - | expression tag |
| Val 1 | - | expression tag |
| Leu 2 | - | expression tag |
| Phe 3 | - | expression tag |
| Ala 4 | - | expression tag |
| Leu 5 | - | expression tag |
| Ile 6 | - | expression tag |
| Cys 7 | - | expression tag |
| Ile 8 | - | expression tag |
| Ala 9 | - | expression tag |
| Val 10 | - | expression tag |
| Ala 11 | - | expression tag |
| Glu 12 | - | expression tag |
| Ala 13 | - | expression tag |
| Gly 682 | Arg 682 | conflict |
| Ser 683 | Arg 683 | conflict |
| Ser 685 | Arg 685 | conflict |
| Pro 817 | Phe 817 | conflict |
| Pro 892 | Ala 892 | conflict |
| Pro 899 | Ala 899 | conflict |
| Pro 942 | Ala 942 | conflict |
| Pro 986 | Lys 986 | conflict |
| Pro 987 | Val 987 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 183316.4 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 570.5 | |
| All* | Total formula weight | 183886.9 |
