8EYO
Crystal Structure of Human Mitochondrial NADP+ Malic Enzyme 3 with NADP bound
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | NADP-dependent malic enzyme, mitochondrial | polymer | 568 | 63829.4 | 2 | UniProt (Q16798) Pfam (PF00390) Pfam (PF03949) | Homo sapiens (human) | NADP-ME,Malic enzyme 3 |
| 2 | C, E (A, B) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 2 | Chemie (NAP) | |||
| 3 | D, F (A, B) | CITRIC ACID | non-polymer | 192.1 | 2 | Chemie (CIT) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 222 | Chemie (HOH) |
Sequence modifications
A, B: 46 - 604 (UniProt: Q16798)
| PDB | External Database | Details |
|---|---|---|
| Met 45 | - | initiating methionine |
| Thr 605 | - | expression tag |
| Arg 606 | - | expression tag |
| Glu 607 | - | expression tag |
| Asn 608 | - | expression tag |
| Leu 609 | - | expression tag |
| Tyr 610 | - | expression tag |
| Phe 611 | - | expression tag |
| Gln 612 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 127658.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1871.1 | |
| All* | Total formula weight | 129529.8 |
