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8EXG

Human Carbonic Anhydrase II bound N-(2-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethoxy)ethyl)-4-sulfamoylbenzamide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Carbonic anhydrase 2polymer26029289.11UniProt (P00918)
Pfam (PF00194)
Homo sapiens (human)Carbonate dehydratase II, Carbonic anhydrase C, CAC, Carbonic anhydrase II, CA-II
2B
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
3C
(A)
(4S)-5-amino-4-{1,3-dioxo-4-[(2-{2-[2-(4-sulfamoylbenzamido)ethoxy]ethoxy}ethyl)amino]-1,3-dihydro-2H-isoindol-2-yl}-5-oxopentanoic acidnon-polymer605.61Chemie (X38)
4D
(A)
MERCURIBENZOIC ACIDnon-polymer321.71Chemie (MBO)
5E
(A)
waterwater18.0140Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight29289.1
Non-Polymers*Number of molecules3
Total formula weight992.7
All*Total formula weight30281.8
*Water molecules are not included.

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PDB entries from 2025-07-16

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