8EUC
Cryo-EM structure of cGMP bound human CNGA3/CNGB3 channel in GDN, transition state 2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Cyclic nucleotide-gated cation channel alpha-3 | polymer | 694 | 78937.9 | 3 | UniProt (Q16281) Pfam (PF00520) Pfam (PF00027) Pfam (PF16526) | Homo sapiens (human) | Cone photoreceptor cGMP-gated channel subunit alpha,Cyclic nucleotide-gated channel alpha-3,CNG channel alpha-3,CNG-3,CNG3 |
| 2 | D (D) | Cyclic nucleotide-gated cation channel beta-3 | polymer | 809 | 92289.5 | 1 | UniProt (Q9NQW8) Pfam (PF00520) Pfam (PF00027) | Homo sapiens (human) | Cone photoreceptor cGMP-gated channel subunit beta,Cyclic nucleotide-gated cation channel modulatory subunit,Cyclic nucleotide-gated channel beta-3,CNG channel beta-3 |
| 3 | E, G, I (A, B, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) | |||
| 4 | F, H, J, K (A, B, C, D) | CYCLIC GUANOSINE MONOPHOSPHATE | non-polymer | 345.2 | 4 | Chemie (PCG) PubChem (177270406) PubChem (136759845) PubChem (135398570) PubChem (135402012) PubChem (135415582) PubChem (135530416) PubChem (135566687) PubChem (135612771) PubChem (136122637) PubChem (136183234) PubChem (136183235) PubChem (136239427) PubChem (136268916) PubChem (136454903) PubChem (136454906) PubChem (136488083) PubChem (136488088) PubChem (136499047) PubChem (136678837) PubChem (137218937) PubChem (137234705) PubChem (137279777) PubChem (138399475) PubChem (164162904) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 329103.3 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 2044.4 | |
| All* | Total formula weight | 331147.7 |
