8ETP
Cryo-EM structure of cGMP bound closed state of human CNGA3/CNGB3 channel in GDN
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Cyclic nucleotide-gated cation channel alpha-3 | polymer | 694 | 78937.9 | 3 | UniProt (Q16281) Pfam (PF00520) Pfam (PF00027) Pfam (PF16526) | Homo sapiens (human) | Cone photoreceptor cGMP-gated channel subunit alpha,Cyclic nucleotide-gated channel alpha-3,CNG channel alpha-3,CNG-3,CNG3 |
| 2 | D (D) | Cyclic nucleotide-gated cation channel beta-3 | polymer | 809 | 92289.5 | 1 | UniProt (Q9NQW8) Pfam (PF00520) Pfam (PF00027) | Homo sapiens (human) | Cone photoreceptor cGMP-gated channel subunit beta,Cyclic nucleotide-gated cation channel modulatory subunit,Cyclic nucleotide-gated channel beta-3,CNG channel beta-3 |
| 3 | E, G, I (A, B, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) | |||
| 4 | F, H, J, K (A, B, C, D) | CYCLIC GUANOSINE MONOPHOSPHATE | non-polymer | 345.2 | 4 | Chemie (PCG) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 329103.3 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 2044.4 | |
| All* | Total formula weight | 331147.7 |
