8ESZ
Structure of mitochondrial complex I from Drosophila melanogaster, Helix-locked state
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | AN | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 | polymer | 142 | 16848.3 | 1 | UniProt (Q9VQD7) Pfam (PF05071) In PDB | Drosophila melanogaster (fruit fly) | |
| 2 | S6 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial | polymer | 126 | 14383.4 | 1 | UniProt (Q9VMU0) Pfam (PF10276) In PDB | Drosophila melanogaster (fruit fly) | |
| 3 | S1 | NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial | polymer | 731 | 78724.3 | 1 | UniProt (Q94511) Pfam (PF13510) Pfam (PF10588) Pfam (PF22117) Pfam (PF22151) Pfam (PF00384) Pfam (PF09326) In PDB | Drosophila melanogaster (fruit fly) | Complex I-75kD,CI-75kD |
| 4 | S3 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial | polymer | 265 | 30013.2 | 1 | UniProt (Q9VZU4) Pfam (PF00329) In PDB | Drosophila melanogaster (fruit fly) | NADH dehydrogenase (Ubiquinone) 30 kDa subunit |
| 5 | V2 | NADH dehydrogenase (Ubiquinone) 24 kDa subunit, isoform A | polymer | 242 | 26814.7 | 1 | UniProt (Q9VX36) Pfam (PF01257) In PDB | Drosophila melanogaster (fruit fly) | NADH dehydrogenase (Ubiquinone) 24 kDa subunit,isoform B |
| 6 | S7 | LD31474p | polymer | 221 | 24622.9 | 1 | UniProt (Q9VXK7) Pfam (PF01058) In PDB | Drosophila melanogaster (fruit fly) | NADH dehydrogenase (Ubiquinone) 20 kDa subunit,isoform A,isoform B,isoform C |
| 7 | S8 | NADH dehydrogenase (ubiquinone) 23 kDa subunit | polymer | 217 | 24610.0 | 1 | UniProt (Q9VF27) Pfam (PF12838) In PDB | Drosophila melanogaster (fruit fly) | |
| 8 | 1 | NADH-ubiquinone oxidoreductase chain 1 | polymer | 315 | 36383.5 | 1 | UniProt (C7DZL9) Pfam (PF00146) In PDB | Drosophila melanogaster (fruit fly) | |
| 9 | 4 | NADH-ubiquinone oxidoreductase chain 4 | polymer | 446 | 51383.0 | 1 | UniProt (Q9MDK5) Pfam (PF01059) Pfam (PF00361) In PDB | Drosophila melanogaster (fruit fly) | |
| 10 | 5 | NADH-ubiquinone oxidoreductase chain 5 | polymer | 577 | 65777.9 | 1 | UniProt (C7DZL4) Pfam (PF06455) Pfam (PF00662) Pfam (PF00361) In PDB | Drosophila melanogaster (fruit fly) | |
| 11 | A8 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 | polymer | 175 | 19873.4 | 1 | UniProt (Q9W125) Pfam (PF06747) In PDB | Drosophila melanogaster (fruit fly) | |
| 12 | A1 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 | polymer | 123 | 14878.2 | 1 | UniProt (A8DYC4) Pfam (PF15879) In PDB | Drosophila melanogaster (fruit fly) | Complex I-MWFE,NADH-ubiquinone oxidoreductase MWFE subunit |
| 13 | AO | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 | polymer | 154 | 17773.6 | 1 | UniProt (Q9W402) Pfam (PF06212) In PDB | Drosophila melanogaster (fruit fly) | |
| 14 | S5 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 | polymer | 101 | 12016.0 | 1 | UniProt (Q7K1C0) Pfam (PF10200) In PDB | Drosophila melanogaster (fruit fly) | Complex I-15 kDa,NADH-ubiquinone oxidoreductase 15 kDa subunit |
| 15 | AM | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 | polymer | 170 | 18433.1 | 1 | UniProt (Q7JYH3) In PDB | Drosophila melanogaster (fruit fly) | Complex I-B14.7,NADH-ubiquinone oxidoreductase subunit B14.7 |
| 16 | BL | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 | polymer | 159 | 18946.4 | 1 | UniProt (Q9VQR2) Pfam (PF10249) In PDB | Drosophila melanogaster (fruit fly) | |
| 17 | B6 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 | polymer | 167 | 19025.9 | 1 | UniProt (Q9V3W2) Pfam (PF09782) In PDB | Drosophila melanogaster (fruit fly) | Complex I-B17,NADH-ubiquinone oxidoreductase B17 subunit |
| 18 | B4 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 | polymer | 113 | 13157.0 | 1 | UniProt (Q6IDF5) Pfam (PF07225) In PDB | Drosophila melanogaster (fruit fly) | Complex I-B15,NADH-ubiquinone oxidoreductase B15 subunit |
| 19 | B7 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 | polymer | 117 | 13905.1 | 1 | UniProt (Q9VXZ0) Pfam (PF05676) In PDB | Drosophila melanogaster (fruit fly) | |
| 20 | B5 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial | polymer | 186 | 22065.1 | 1 | UniProt (Q9VTU2) Pfam (PF09781) In PDB | Drosophila melanogaster (fruit fly) | Complex I-SGDH,NADH-ubiquinone oxidoreductase SGDH subunit |
| 21 | B9 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 | polymer | 144 | 17416.8 | 1 | UniProt (Q9VJZ4) Pfam (PF05347) In PDB | Drosophila melanogaster (fruit fly) | |
| 22 | BM | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial | polymer | 150 | 16988.0 | 1 | UniProt (Q9V3L7) Pfam (PF10183) In PDB | Drosophila melanogaster (fruit fly) | Complex I-ESSS,NADH-ubiquinone oxidoreductase ESSS subunit |
| 23 | B8 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial | polymer | 175 | 20229.9 | 1 | UniProt (Q9W3X7) Pfam (PF05821) In PDB | Drosophila melanogaster (fruit fly) | Complex I-ASHI,NADH-ubiquinone oxidoreductase ASHI subunit |
| 24 | B3 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 | polymer | 110 | 12113.6 | 1 | UniProt (Q9W2E8) Pfam (PF08122) In PDB | Drosophila melanogaster (fruit fly) | Complex I-B12,NADH-ubiquinone oxidoreductase B12 subunit |
| 25 | AC, AB | Acyl carrier protein, mitochondrial | polymer | 152 | 17258.0 | 2 | UniProt (Q94519) Pfam (PF00550) In PDB | Drosophila melanogaster (fruit fly) | ACP,NADH-ubiquinone oxidoreductase 9.6 kDa subunit,NADH-ubiquinone oxidoreductase acyl-carrier subunit |
| 26 | C2 | NADH dehydrogenase [ubiquinone] 1 subunit C2 | polymer | 116 | 12925.8 | 1 | UniProt (Q9VQM2) Pfam (PF06374) In PDB | Drosophila melanogaster (fruit fly) | |
| 27 | B1 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 | polymer | 56 | 6232.3 | 1 | UniProt (Q9W3N7) Pfam (PF08040) In PDB | Drosophila melanogaster (fruit fly) | Complex I-MNLL,NADH-ubiquinone oxidoreductase MNLL subunit |
| 28 | S4 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial | polymer | 183 | 20710.4 | 1 | UniProt (Q9VWI0) Pfam (PF04800) In PDB | Drosophila melanogaster (fruit fly) | |
| 29 | A9 | NADH dehydrogenase (Ubiquinone) 39 kDa subunit, isoform A | polymer | 416 | 46891.7 | 1 | UniProt (Q9VPE2) Pfam (PF01370) In PDB | Drosophila melanogaster (fruit fly) | NADH dehydrogenase (Ubiquinone) 39 kDa subunit,isoform B,TB01457p1 |
| 30 | B2 | GEO11417p1 | polymer | 94 | 10758.3 | 1 | UniProt (Q7PL91) Pfam (PF14813) In PDB | Drosophila melanogaster (fruit fly) | NADH dehydrogenase (Ubiquinone) AGGG subunit,isoform A,isoform B,RH18150p |
| 31 | S2 | Complex I-49kD | polymer | 468 | 52986.0 | 1 | UniProt (Q9V4E0) Pfam (PF00346) In PDB | Drosophila melanogaster (fruit fly) | NADH-ubiquinone oxidoreductase 49 kDa subunit |
| 32 | V3 | NADH dehydrogenase [ubiquinone] flavoprotein 3 | polymer | 37 | 3166.9 | 1 | Drosophila melanogaster (fruit fly) | ||
| 33 | V1 | NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial | polymer | 474 | 51898.7 | 1 | UniProt (Q9VMI3) Pfam (PF01512) Pfam (PF22461) Pfam (PF10589) In PDB | Drosophila melanogaster (fruit fly) | |
| 34 | 2 | NADH-ubiquinone oxidoreductase chain 2 | polymer | 341 | 39839.9 | 1 | UniProt (P03896) Pfam (PF00361) Pfam (PF06444) In PDB | Drosophila melanogaster (fruit fly) | NADH dehydrogenase subunit 2 |
| 35 | A7 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 | polymer | 103 | 11562.1 | 1 | UniProt (O97418) Pfam (PF07347) In PDB | Drosophila melanogaster (fruit fly) | Complex I-B14.5a,NADH-ubiquinone oxidoreductase subunit B14.5a |
| 36 | A3 | RH45008p | polymer | 77 | 8412.5 | 1 | UniProt (Q9W380) In PDB | Drosophila melanogaster (fruit fly) | Uncharacterized protein,isoform A,isoform B |
| 37 | 4L | NADH-ubiquinone oxidoreductase chain 4L | polymer | 96 | 11363.9 | 1 | UniProt (P18934) Pfam (PF00420) In PDB | Drosophila melanogaster (fruit fly) | NADH dehydrogenase subunit 4L |
| 38 | 6 | NADH-ubiquinone oxidoreductase chain 6 | polymer | 174 | 20083.6 | 1 | UniProt (P18933) Pfam (PF00499) In PDB | Drosophila melanogaster (fruit fly) | NADH dehydrogenase subunit 6 |
| 39 | 3 | NADH-ubiquinone oxidoreductase chain 3 | polymer | 117 | 13572.5 | 1 | UniProt (P18930) Pfam (PF00507) In PDB | Drosophila melanogaster (fruit fly) | NADH dehydrogenase subunit 3 |
| 40 | A5 | NADH dehydrogenase (Ubiquinone) 13 kDa B subunit | polymer | 124 | 13808.1 | 1 | UniProt (Q9VTB4) Pfam (PF04716) In PDB | Drosophila melanogaster (fruit fly) | RH11203p |
| 41 | AL | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial | polymer | 407 | 46955.5 | 1 | UniProt (P91929) Pfam (PF01712) In PDB | Drosophila melanogaster (fruit fly) | Complex I-42kD,CI-42kD,NADH-ubiquinone oxidoreductase 42 kDa subunit |
| 42 | A6 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 | polymer | 124 | 14921.4 | 1 | UniProt (Q7JZK1) Pfam (PF05347) In PDB | Drosophila melanogaster (fruit fly) | Complex I-B14,NADH-ubiquinone oxidoreductase B14 subunit |
| 43 | 6, 3, B6, B5, AN... | CARDIOLIPIN | non-polymer | 1464.0 | 8 | Chemie (CDL) | |||
| 44 | AM, S7, B6, 1, 4... | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE | non-polymer | 790.1 | 12 | Chemie (PC1) | |||
| 45 | S6 | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 46 | S8, S1, V1, S7 | IRON/SULFUR CLUSTER | non-polymer | 351.6 | 6 | Chemie (SF4) | |||
| 47 | S1, V2 | FE2/S2 (INORGANIC) CLUSTER | non-polymer | 175.8 | 2 | Chemie (FES) | |||
| 48 | S7, 6, B6, 3, B4... | 1,2-Distearoyl-sn-glycerophosphoethanolamine | non-polymer | 748.1 | 24 | Chemie (3PE) | |||
| 49 | 1 | UBIQUINONE-10 | non-polymer | 863.3 | 1 | Chemie (U10) | |||
| 50 | B5, C2, AO | TETRADECANE | non-polymer | 198.4 | 3 | Chemie (C14) | |||
| 51 | AB, AC | S-[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate | non-polymer | 568.7 | 2 | Chemie (ZMP) | |||
| 52 | B1 | N-OCTANE | non-polymer | 114.2 | 1 | Chemie (OCT) | |||
| 53 | B1, A9, A3 | DODECANE | non-polymer | 170.3 | 4 | Chemie (D12) | |||
| 54 | A9 | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 1 | Chemie (NDP) | |||
| 55 | V1 | FLAVIN MONONUCLEOTIDE | non-polymer | 456.3 | 1 | Chemie (FMN) | |||
| 56 | 6 | (2R)-3-{[(S)-hydroxy(3-methylbutoxy)phosphoryl]oxy}-2-(octanoyloxy)propyl decanoate | non-polymer | 522.7 | 1 | Chemie (WSF) | |||
| 57 | AL | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 1 | Chemie (DGT) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 43 |
| Total formula weight | 1026988.6 | |
| Non-Polymers* | Number of molecules | 68 |
| Total formula weight | 47297.6 | |
| All* | Total formula weight | 1074286.2 |
