8ESZ
Structure of mitochondrial complex I from Drosophila melanogaster, Helix-locked state
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (AN) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 | polymer | 142 | 16848.3 | 1 | UniProt (Q9VQD7) Pfam (PF05071) | Drosophila melanogaster (fruit fly) | |
| 2 | B (S6) | NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial | polymer | 126 | 14383.4 | 1 | UniProt (Q9VMU0) Pfam (PF10276) | Drosophila melanogaster (fruit fly) | |
| 3 | C (S1) | NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial | polymer | 731 | 78724.3 | 1 | UniProt (Q94511) Pfam (PF13510) Pfam (PF10588) Pfam (PF22117) Pfam (PF22151) Pfam (PF00384) Pfam (PF09326) | Drosophila melanogaster (fruit fly) | Complex I-75kD,CI-75kD |
| 4 | D (S3) | NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial | polymer | 265 | 30013.2 | 1 | UniProt (Q9VZU4) Pfam (PF00329) | Drosophila melanogaster (fruit fly) | NADH dehydrogenase (Ubiquinone) 30 kDa subunit |
| 5 | E (V2) | NADH dehydrogenase (Ubiquinone) 24 kDa subunit, isoform A | polymer | 242 | 26814.7 | 1 | UniProt (Q9VX36) Pfam (PF01257) | Drosophila melanogaster (fruit fly) | NADH dehydrogenase (Ubiquinone) 24 kDa subunit,isoform B |
| 6 | F (S7) | LD31474p | polymer | 221 | 24622.9 | 1 | UniProt (Q9VXK7) Pfam (PF01058) | Drosophila melanogaster (fruit fly) | NADH dehydrogenase (Ubiquinone) 20 kDa subunit,isoform A,isoform B,isoform C |
| 7 | G (S8) | NADH dehydrogenase (ubiquinone) 23 kDa subunit | polymer | 217 | 24610.0 | 1 | UniProt (Q9VF27) Pfam (PF12838) | Drosophila melanogaster (fruit fly) | |
| 8 | H (1) | NADH-ubiquinone oxidoreductase chain 1 | polymer | 315 | 36383.5 | 1 | UniProt (C7DZL9) Pfam (PF00146) | Drosophila melanogaster (fruit fly) | |
| 9 | I (4) | NADH-ubiquinone oxidoreductase chain 4 | polymer | 446 | 51383.0 | 1 | UniProt (Q9MDK5) Pfam (PF01059) Pfam (PF00361) | Drosophila melanogaster (fruit fly) | |
| 10 | J (5) | NADH-ubiquinone oxidoreductase chain 5 | polymer | 577 | 65777.9 | 1 | UniProt (C7DZL4) Pfam (PF06455) Pfam (PF00662) Pfam (PF00361) | Drosophila melanogaster (fruit fly) | |
| 11 | K (A8) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 | polymer | 175 | 19873.4 | 1 | UniProt (Q9W125) Pfam (PF06747) | Drosophila melanogaster (fruit fly) | |
| 12 | L (A1) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 | polymer | 123 | 14878.2 | 1 | UniProt (A8DYC4) Pfam (PF15879) | Drosophila melanogaster (fruit fly) | Complex I-MWFE,NADH-ubiquinone oxidoreductase MWFE subunit |
| 13 | M (AO) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 | polymer | 154 | 17773.6 | 1 | UniProt (Q9W402) Pfam (PF06212) | Drosophila melanogaster (fruit fly) | |
| 14 | N (S5) | NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 | polymer | 101 | 12016.0 | 1 | UniProt (Q7K1C0) Pfam (PF10200) | Drosophila melanogaster (fruit fly) | Complex I-15 kDa,NADH-ubiquinone oxidoreductase 15 kDa subunit |
| 15 | O (AM) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 | polymer | 170 | 18433.1 | 1 | UniProt (Q7JYH3) | Drosophila melanogaster (fruit fly) | Complex I-B14.7,NADH-ubiquinone oxidoreductase subunit B14.7 |
| 16 | P (BL) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 | polymer | 159 | 18946.4 | 1 | UniProt (Q9VQR2) Pfam (PF10249) | Drosophila melanogaster (fruit fly) | |
| 17 | Q (B6) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 | polymer | 167 | 19025.9 | 1 | UniProt (Q9V3W2) Pfam (PF09782) | Drosophila melanogaster (fruit fly) | Complex I-B17,NADH-ubiquinone oxidoreductase B17 subunit |
| 18 | R (B4) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 | polymer | 113 | 13157.0 | 1 | UniProt (Q6IDF5) Pfam (PF07225) | Drosophila melanogaster (fruit fly) | Complex I-B15,NADH-ubiquinone oxidoreductase B15 subunit |
| 19 | S (B7) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 | polymer | 117 | 13905.1 | 1 | UniProt (Q9VXZ0) Pfam (PF05676) | Drosophila melanogaster (fruit fly) | |
| 20 | T (B5) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial | polymer | 186 | 22065.1 | 1 | UniProt (Q9VTU2) Pfam (PF09781) | Drosophila melanogaster (fruit fly) | Complex I-SGDH,NADH-ubiquinone oxidoreductase SGDH subunit |
| 21 | U (B9) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 | polymer | 144 | 17416.8 | 1 | UniProt (Q9VJZ4) Pfam (PF05347) | Drosophila melanogaster (fruit fly) | |
| 22 | V (BM) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial | polymer | 150 | 16988.0 | 1 | UniProt (Q9V3L7) Pfam (PF10183) | Drosophila melanogaster (fruit fly) | Complex I-ESSS,NADH-ubiquinone oxidoreductase ESSS subunit |
| 23 | W (B8) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial | polymer | 175 | 20229.9 | 1 | UniProt (Q9W3X7) Pfam (PF05821) | Drosophila melanogaster (fruit fly) | Complex I-ASHI,NADH-ubiquinone oxidoreductase ASHI subunit |
| 24 | X (B3) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 | polymer | 110 | 12113.6 | 1 | UniProt (Q9W2E8) Pfam (PF08122) | Drosophila melanogaster (fruit fly) | Complex I-B12,NADH-ubiquinone oxidoreductase B12 subunit |
| 25 | QA, Y (AC, AB) | Acyl carrier protein, mitochondrial | polymer | 152 | 17258.0 | 2 | UniProt (Q94519) Pfam (PF00550) | Drosophila melanogaster (fruit fly) | ACP,NADH-ubiquinone oxidoreductase 9.6 kDa subunit,NADH-ubiquinone oxidoreductase acyl-carrier subunit |
| 26 | Z (C2) | NADH dehydrogenase [ubiquinone] 1 subunit C2 | polymer | 116 | 12925.8 | 1 | UniProt (Q9VQM2) Pfam (PF06374) | Drosophila melanogaster (fruit fly) | |
| 27 | AA (B1) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 | polymer | 56 | 6232.3 | 1 | UniProt (Q9W3N7) Pfam (PF08040) | Drosophila melanogaster (fruit fly) | Complex I-MNLL,NADH-ubiquinone oxidoreductase MNLL subunit |
| 28 | BA (S4) | NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial | polymer | 183 | 20710.4 | 1 | UniProt (Q9VWI0) Pfam (PF04800) | Drosophila melanogaster (fruit fly) | |
| 29 | CA (A9) | NADH dehydrogenase (Ubiquinone) 39 kDa subunit, isoform A | polymer | 416 | 46891.7 | 1 | UniProt (Q9VPE2) Pfam (PF01370) | Drosophila melanogaster (fruit fly) | NADH dehydrogenase (Ubiquinone) 39 kDa subunit,isoform B,TB01457p1 |
| 30 | DA (B2) | GEO11417p1 | polymer | 94 | 10758.3 | 1 | UniProt (Q7PL91) Pfam (PF14813) | Drosophila melanogaster (fruit fly) | NADH dehydrogenase (Ubiquinone) AGGG subunit,isoform A,isoform B,RH18150p |
| 31 | EA (S2) | Complex I-49kD | polymer | 468 | 52986.0 | 1 | UniProt (Q9V4E0) Pfam (PF00346) | Drosophila melanogaster (fruit fly) | NADH-ubiquinone oxidoreductase 49 kDa subunit |
| 32 | FA (V3) | NADH dehydrogenase [ubiquinone] flavoprotein 3 | polymer | 37 | 3166.9 | 1 | Drosophila melanogaster (fruit fly) | ||
| 33 | GA (V1) | NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial | polymer | 474 | 51898.7 | 1 | UniProt (Q9VMI3) Pfam (PF01512) Pfam (PF22461) Pfam (PF10589) | Drosophila melanogaster (fruit fly) | |
| 34 | HA (2) | NADH-ubiquinone oxidoreductase chain 2 | polymer | 341 | 39839.9 | 1 | UniProt (P03896) Pfam (PF00361) Pfam (PF06444) | Drosophila melanogaster (fruit fly) | NADH dehydrogenase subunit 2 |
| 35 | IA (A7) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 | polymer | 103 | 11562.1 | 1 | UniProt (O97418) Pfam (PF07347) | Drosophila melanogaster (fruit fly) | Complex I-B14.5a,NADH-ubiquinone oxidoreductase subunit B14.5a |
| 36 | JA (A3) | RH45008p | polymer | 77 | 8412.5 | 1 | UniProt (Q9W380) | Drosophila melanogaster (fruit fly) | Uncharacterized protein,isoform A,isoform B |
| 37 | KA (4L) | NADH-ubiquinone oxidoreductase chain 4L | polymer | 96 | 11363.9 | 1 | UniProt (P18934) Pfam (PF00420) | Drosophila melanogaster (fruit fly) | NADH dehydrogenase subunit 4L |
| 38 | LA (6) | NADH-ubiquinone oxidoreductase chain 6 | polymer | 174 | 20083.6 | 1 | UniProt (P18933) Pfam (PF00499) | Drosophila melanogaster (fruit fly) | NADH dehydrogenase subunit 6 |
| 39 | MA (3) | NADH-ubiquinone oxidoreductase chain 3 | polymer | 117 | 13572.5 | 1 | UniProt (P18930) Pfam (PF00507) | Drosophila melanogaster (fruit fly) | NADH dehydrogenase subunit 3 |
| 40 | NA (A5) | NADH dehydrogenase (Ubiquinone) 13 kDa B subunit | polymer | 124 | 13808.1 | 1 | UniProt (Q9VTB4) Pfam (PF04716) | Drosophila melanogaster (fruit fly) | RH11203p |
| 41 | OA (AL) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial | polymer | 407 | 46955.5 | 1 | UniProt (P91929) Pfam (PF01712) | Drosophila melanogaster (fruit fly) | Complex I-42kD,CI-42kD,NADH-ubiquinone oxidoreductase 42 kDa subunit |
| 42 | PA (A6) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 | polymer | 124 | 14921.4 | 1 | UniProt (Q7JZK1) Pfam (PF05347) | Drosophila melanogaster (fruit fly) | Complex I-B14,NADH-ubiquinone oxidoreductase B14 subunit |
| 43 | BD, CD, EC, GC, HC... (6, 3, B6, B5, AN...) | CARDIOLIPIN | non-polymer | 1464.0 | 8 | Chemie (CDL) | |||
| 44 | AC, BB, BC, DC, EB... (AM, S7, B6, 1, 4...) | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE | non-polymer | 790.1 | 12 | Chemie (PC1) | |||
| 45 | TA (S6) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 46 | CB, DB, UA, UC, VA... (S8, S1, V1, S7) | IRON/SULFUR CLUSTER | non-polymer | 351.6 | 6 | Chemie (SF4) | |||
| 47 | WA, XA (S1, V2) | FE2/S2 (INORGANIC) CLUSTER | non-polymer | 175.8 | 2 | Chemie (FES) | |||
| 48 | AB, AD, CC, DD, ED... (S7, 6, B6, 3, B4...) | 1,2-Distearoyl-sn-glycerophosphoethanolamine | non-polymer | 748.1 | 24 | Chemie (3PE) | |||
| 49 | FB (1) | UBIQUINONE-10 | non-polymer | 863.3 | 1 | Chemie (U10) | |||
| 50 | IC, LC, VB (B5, C2, AO) | TETRADECANE | non-polymer | 198.4 | 3 | Chemie (C14) | |||
| 51 | GD, JC (AB, AC) | S-[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate | non-polymer | 568.7 | 2 | Chemie (ZMP) | |||
| 52 | MC (B1) | N-OCTANE | non-polymer | 114.2 | 1 | Chemie (OCT) | |||
| 53 | NC, RC, SC, YC (B1, A9, A3) | DODECANE | non-polymer | 170.3 | 4 | Chemie (D12) | |||
| 54 | QC (A9) | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 1 | Chemie (NDP) | |||
| 55 | TC (V1) | FLAVIN MONONUCLEOTIDE | non-polymer | 456.3 | 1 | Chemie (FMN) | |||
| 56 | ZC (6) | (2R)-3-{[(S)-hydroxy(3-methylbutoxy)phosphoryl]oxy}-2-(octanoyloxy)propyl decanoate | non-polymer | 522.7 | 1 | Chemie (WSF) | |||
| 57 | FD (AL) | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 1 | Chemie (DGT) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 43 |
| Total formula weight | 1026988.6 | |
| Non-Polymers* | Number of molecules | 68 |
| Total formula weight | 47297.6 | |
| All* | Total formula weight | 1074286.2 |
