8EQV
Cryo-EM structure of PRC2 in complex with the long isoform of AEBP2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Histone-binding protein RBBP4 | polymer | 425 | 47709.5 | 1 | UniProt (Q09028) Pfam (PF12265) Pfam (PF00400) | Homo sapiens (human) | Chromatin assembly factor 1 subunit C,CAF-1 subunit C,Chromatin assembly factor I p48 subunit,CAF-I p48,Nucleosome-remodeling factor subunit RBAP48,Retinoblastoma-binding protein 4,RBBP-4,Retinoblastoma-binding protein p48 |
| 2 | B (C) | Zinc finger protein AEBP2 | polymer | 517 | 54535.5 | 1 | UniProt (Q6ZN18) Pfam (PF26014) | Homo sapiens (human) | Adipocyte enhancer-binding protein 2,AE-binding protein 2 |
| 3 | C (E) | Polycomb protein EED | polymer | 441 | 50267.7 | 1 | UniProt (O75530) Pfam (PF00400) | Homo sapiens (human) | hEED,Embryonic ectoderm development protein,WD protein associating with integrin cytoplasmic tails 1,WAIT-1 |
| 4 | D (D) | Histone-lysine N-methyltransferase EZH2 | polymer | 746 | 85492.3 | 1 | UniProt (Q15910) Pfam (PF11616) Pfam (PF18118) Pfam (PF21358) Pfam (PF18264) Pfam (PF00856) | Homo sapiens (human) | ENX-1,Enhancer of zeste homolog 2,Lysine N-methyltransferase 6 |
| 5 | E (B) | Polycomb protein SUZ12 | polymer | 739 | 83181.9 | 1 | UniProt (Q15022) Pfam (PF23320) Pfam (PF09733) | Homo sapiens (human) | Chromatin precipitated E2F target 9 protein,ChET 9 protein,Joined to JAZF1 protein,Suppressor of zeste 12 protein homolog |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 321186.9 | |
| All* | Total formula weight | 321186.9 |
