8EPC
Crystal structure of human coagulation factor IXa (S195A), apo-form
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Coagulation factor IXa light chain | polymer | 65 | 7267.3 | 1 | UniProt (P00740) Pfam (PF14670) | Homo sapiens (human) | |
| 2 | B (B) | Coagulation factor IXa heavy chain | polymer | 235 | 26174.8 | 1 | UniProt (P00740) Pfam (PF00089) | Homo sapiens (human) | |
| 3 | C (B) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 4 | D, E (A, B) | water | water | 18.0 | 4 | Chemie (HOH) |
Sequence modifications
A: 84 - 144 (UniProt: P00740)
B: 16 - 245 (UniProt: P00740)
| PDB | External Database | Details |
|---|---|---|
| Arg 145 | - | insertion |
| Arg 146 | - | insertion |
| Lys 147 | - | insertion |
| Arg 148 | - | insertion |
| PDB | External Database | Details |
|---|---|---|
| Ala 195 | Ser 411 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 33442.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 40.1 | |
| All* | Total formula weight | 33482.2 |
