8EPA
Structure of interleukin receptor common gamma chain (IL2Rgamma) in complex with two antibodies
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | I | Cytokine receptor common subunit gamma | polymer | 268 | 31617.1 | 1 | UniProt (P31785) Pfam (PF22012) Pfam (PF21605) In PDB | Homo sapiens (human) | Interleukin-2 receptor subunit gamma,IL-2 receptor subunit gamma,IL-2R subunit gamma,IL-2RG,gammaC,p64 |
2 | H | REGN7257 Fab heavy chain | polymer | 220 | 23607.5 | 1 | Mus musculus | ||
3 | L | REGN7257 Fab light chain | polymer | 214 | 23541.1 | 1 | Mus musculus | ||
4 | A | REGN9432 Fab heavy chain | polymer | 221 | 23323.0 | 1 | Mus musculus | ||
5 | B | REGN9432 Fab light chain | polymer | 214 | 23247.8 | 1 | Mus musculus | ||
6 | C | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) |
Sequence modifications
I: 1 - 240 (UniProt: P31785)
PDB | External Database | Details |
---|---|---|
Glu 241 | - | expression tag |
Gln 242 | - | expression tag |
Lys 243 | - | expression tag |
Leu 244 | - | expression tag |
Ile 245 | - | expression tag |
Ser 246 | - | expression tag |
Glu 247 | - | expression tag |
Glu 248 | - | expression tag |
Asp 249 | - | expression tag |
Leu 250 | - | expression tag |
Gly 251 | - | expression tag |
Gly 252 | - | expression tag |
Glu 253 | - | expression tag |
Gln 254 | - | expression tag |
Lys 255 | - | expression tag |
Leu 256 | - | expression tag |
Ile 257 | - | expression tag |
Ser 258 | - | expression tag |
Glu 259 | - | expression tag |
Glu 260 | - | expression tag |
Asp 261 | - | expression tag |
Leu 262 | - | expression tag |
His 263 | - | expression tag |
His 264 | - | expression tag |
His 265 | - | expression tag |
His 266 | - | expression tag |
His 267 | - | expression tag |
His 268 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 5 |
Total formula weight | 125336.5 | |
Branched | Number of molecules | 1 |
Total formula weight | 424.4 | |
All* | Total formula weight | 125760.9 |