8EMX

Phospholipase C beta 3 (PLCb3) in complex with Gbg on lipid nanodiscs

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3	polymer	1234	139055.6	1	UniProt (Q01970) Pfam (PF17787) Pfam (PF22631) Pfam (PF00388) Pfam (PF00387) Pfam (PF00168) Pfam (PF08703) In PDB	Homo sapiens (human)	Phosphoinositide phospholipase C-beta-3,Phospholipase C-beta-3,PLC-beta-3
2	B, C	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1	polymer	340	37416.9	2	UniProt (P62873) Pfam (PF00400) In PDB	Homo sapiens (human)	Transducin beta chain 1
3	G, D	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2	polymer	70	7717.9	2	UniProt (P59768) Pfam (PF00631) In PDB	Homo sapiens (Human)	G gamma-I
4	A	CALCIUM ION	non-polymer		40.1	1	Chemie (CA)

Sequence modifications

A: 9 - 1234 (UniProt: Q01970)

PDB	External Database	Details
Gly 1	-	expression tag
Pro 2	-	expression tag
Ser 3	-	expression tag
Arg 4	-	expression tag
Ala 5	-	expression tag
Ser 6	-	expression tag
Thr 7	-	expression tag
Met 8	-	expression tag

G, D: 1 - 68 (UniProt: P59768)

PDB	External Database	Details
Gly -1	-	expression tag
Pro 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	229325.3
Non-Polymers*	Number of molecules	1
	Total formula weight	40.1
All*	Total formula weight	229365.4

*Water molecules are not included.