8EM8
Co-crystal structure of the cGMP-dependent protein kinase PKG from Plasmodium falciparum in complex with RY-1-165
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | cGMP-dependent protein kinase | polymer | 853 | 97814.6 | 1 | UniProt (Q8I719) Pfam (PF00027) Pfam (PF00069) In PDB | Plasmodium falciparum (isolate 3D7) | PfPKG |
| 2 | U | unidentified peptide fragment | polymer | 4 | 358.4 | 1 | Plasmodium falciparum (isolate 3D7) | ||
| 3 | A | [(3R)-3-{[(4M)-4-(4-cyclopropyl-2-phenyl-1H-imidazol-1-yl)pyrimidin-2-yl]amino}pyrrolidin-1-yl](1,3-thiazol-2-yl)methanone | non-polymer | 457.6 | 1 | Chemie (WLK) | |||
| 4 | A | UNKNOWN ATOM OR ION | non-polymer | 4 | Chemie (UNX) | ||||
| 5 | water | water | 18.0 | 152 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 98173.0 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 457.6 | |
| All* | Total formula weight | 98630.5 |
