8EL2

SARS-CoV-2 RBD bound to neutralizing antibody Fab ICO-hu23

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	H, I	Fab ICO-hu23 Heavy Chain	polymer	234	25479.6	2		Homo sapiens (Human)
2	L, K	Fab ICO-hu23 Light Chain	polymer	216	22802.1	2		Homo sapiens (Human)
3	A, B	Spike protein S1	polymer	231	26109.4	2	UniProt (P0DTC2) Pfam (PF09408) In PDB	Severe acute respiratory syndrome coronavirus 2
4	L, B	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
5	L, K	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
6	A, B	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)

Sequence modifications

A, B: 319 - 541 (UniProt: P0DTC2)

PDB	External Database	Details
Ala 317	-	expression tag
Ser 318	-	expression tag
His 542	-	expression tag
His 543	-	expression tag
His 544	-	expression tag
His 545	-	expression tag
His 546	-	expression tag
His 547	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	148782.1
Non-Polymers*	Number of molecules	6
	Total formula weight	757.4
All*	Total formula weight	149539.6

*Water molecules are not included.