8EK9
Crystal structure of the class A carbapenemase CRH-1 in complex with avibactam at 1.4 Angstrom resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Beta-lactamase | polymer | 270 | 28685.6 | 1 | UniProt (A0A1W0D7S2) Pfam (PF00144) Pfam (PF13354) In PDB | Chromobacterium haemolyticum | |
| 2 | A | (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide | non-polymer | 267.3 | 1 | Chemie (NXL) | |||
| 3 | water | water | 18.0 | 272 | Chemie (HOH) |
Sequence modifications
A: 24 - 293 (UniProt: A0A1W0D7S2)
| PDB | External Database | Details |
|---|---|---|
| Thr 150 | Ala 147 | engineered mutation |
| Ile 173 | Val 170 | engineered mutation |
| Arg 175 | Gly 172 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 28685.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 267.3 | |
| All* | Total formula weight | 28952.8 |
