8EJX
Crystal structure of human cyclophilin D (CypD) with in complex with the covalently bound Ebselen inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Peptidyl-prolyl cis-trans isomerase F, mitochondrial | polymer | 165 | 17755.2 | 1 | UniProt (P30405) Pfam (PF00160) In PDB | Homo sapiens (human) | PPIase F,Cyclophilin D,CyP-D,CypD,Cyclophilin F,Mitochondrial cyclophilin,CyP-M,Rotamase F |
| 2 | A | N-phenyl-2-selanylbenzamide | non-polymer | 276.2 | 1 | Chemie (9JT) | |||
| 3 | water | water | 18.0 | 115 | Chemie (HOH) |
Sequence modifications
A: 1 - 165 (UniProt: P30405)
| PDB | External Database | Details |
|---|---|---|
| Ile 133 | Lys 175 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 17755.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 276.2 | |
| All* | Total formula weight | 18031.4 |
