8EJ8
Human PU.1 ETS-Domain (165-270) Q226E Mutant Bound to d(AATAAAAGGAAGTGGG)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (C) | DNA (5'-D(*AP*AP*TP*AP*AP*AP*AP*GP*GP*AP*AP*GP*TP*GP*GP*G)-3') | polymer | 16 | 5044.3 | 1 | synthetic construct | ||
| 2 | B (D) | DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*TP*TP*TP*TP*AP*T)-3') | polymer | 16 | 4750.1 | 1 | synthetic construct | ||
| 3 | C (F) | Transcription factor PU.1 | polymer | 106 | 12437.6 | 1 | UniProt (P17947) Pfam (PF00178) | Homo sapiens (human) | 31 kDa-transforming protein |
| 4 | D (F) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | E, F, G (C, D, F) | water | water | 18.0 | 279 | Chemie (HOH) |
Sequence modifications
F: 165 - 270 (UniProt: P17947)
| PDB | External Database | Details |
|---|---|---|
| Glu 226 | Gln 226 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 22232.0 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 92.1 | |
| All* | Total formula weight | 22324.1 |
