8EIA
Crystal structure of beta-catenin and the MDM2 p53-binding domain in complex with H333, a Helicon Polypeptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Catenin beta-1 | polymer | 533 | 58139.3 | 1 | UniProt (P35222) Pfam (PF00514) | Homo sapiens (human) | Beta-catenin |
| 2 | B (B) | E3 ubiquitin-protein ligase Mdm2 | polymer | 95 | 11099.0 | 1 | UniProt (Q00987) Pfam (PF02201) | Homo sapiens (human) | Double minute 2 protein,Hdm2,Oncoprotein Mdm2,RING-type E3 ubiquitin transferase Mdm2,p53-binding protein Mdm2 |
| 3 | C (C) | H333 | polymer | 23 | 2623.9 | 1 | synthetic construct | ||
| 4 | D (C) | N,N'-(1,4-phenylene)diacetamide | non-polymer | 192.2 | 1 | Chemie (WHL) |
Sequence modifications
A: 134 - 665 (UniProt: P35222)
| PDB | External Database | Details |
|---|---|---|
| Gly 133 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 71862.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 192.2 | |
| All* | Total formula weight | 72054.4 |
