8EI5
Crystal structure of the WWP2 HECT domain in complex with H301, a Helicon Polypeptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | NEDD4-like E3 ubiquitin-protein ligase WWP2 | polymer | 376 | 44925.4 | 4 | UniProt (O00308) Pfam (PF00632) | Homo sapiens (human) | Atrophin-1-interacting protein 2,AIP2,HECT-type E3 ubiquitin transferase WWP2,WW domain-containing protein 2 |
| 2 | E, F, G, H (E, F, G, H) | H301 | polymer | 19 | 1884.2 | 4 | synthetic construct | ||
| 3 | BA, I, S, X (D, A, B, C) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 4 | J, K, L, T, U (A, B) | GLYCEROL | non-polymer | 92.1 | 5 | Chemie (GOL) | |||
| 5 | AA, CA, DA, EA, FA... (C, D, E, F, A...) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 17 | Chemie (EDO) | |||
| 6 | GA, IA, KA, LA (E, F, G, H) | N,N'-(1,4-phenylene)diacetamide | non-polymer | 192.2 | 4 | Chemie (WHL) | |||
| 7 | MA, NA, OA, PA (A, B, C, D) | water | water | 18.0 | 319 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 492 - 865 (UniProt: O00308)
| PDB | External Database | Details |
|---|---|---|
| Gly 490 | - | expression tag |
| Pro 491 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 187238.5 | |
| Non-Polymers* | Number of molecules | 30 |
| Total formula weight | 2546.1 | |
| All* | Total formula weight | 189784.6 |
