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8EEC

Crystal structure of HPK1 citron-homology domain

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AIsoform 2 of Mitogen-activated protein kinase kinase kinase kinase 1polymer34337399.31UniProt (Q92918)
Pfam (PF00780)
In PDB
Homo sapiens (human)Hematopoietic progenitor kinase,MAPK/ERK kinase kinase kinase 1,MEK kinase kinase 1,MEKKK 1
2APHOSPHATE IONnon-polymer95.06Chemie (PO4)
3waterwater18.094Chemie (HOH)
Sequence modifications
A: 481 - 821 (UniProt: Q92918)
PDBExternal DatabaseDetails
Gly 479-expression tag
Ser 480-expression tag
Ala 593Arg 593conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight37399.3
Non-Polymers*Number of molecules6
Total formula weight569.8
All*Total formula weight37969.1
*Water molecules are not included.

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PDB entries from 2024-05-15

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