8EDE

Crystal structure of covalent inhibitor 2-chloro-N'-(N-(4-chlorophenyl)-N-methylglycyl)acetohydrazide bound to Ubiquitin C-terminal Hydrolase-L1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Ubiquitin carboxyl-terminal hydrolase isozyme L1	polymer	223	24855.3	2	UniProt (P09936) Pfam (PF01088)	Homo sapiens (human)	UCH-L1,Neuron cytoplasmic protein 9.5,PGP 9.5,PGP9.5,Ubiquitin thioesterase L1
2	C, F (A, B)	2-[(4-chlorophenyl)-methyl-amino]-~{N}'-ethanoyl-ethanehydrazide	non-polymer		255.7	2	Chemie (WEU)
3	D, E, G, H (A, B)	SULFATE ION	non-polymer		96.1	4	Chemie (SO4)
4	I, J (A, B)	water	water		18.0	208	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	49710.7
Non-Polymers*	Number of molecules	6
	Total formula weight	895.7
All*	Total formula weight	50606.3

*Water molecules are not included.