8E67
ETV6 H396Y variant bound to DNA containing the sequence GGAT
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D, G, J (B, D, G, J) | GGAT-containing 15 bp DNA | polymer | 15 | 4683.1 | 4 | synthetic construct | ||
| 2 | B, E, H, K (C, E, H, K) | Complementary 15 bp strand | polymer | 15 | 4495.9 | 4 | synthetic construct | ||
| 3 | C, F, I, L (A, F, I, L) | Transcription factor ETV6 | polymer | 101 | 12337.2 | 4 | UniProt (E9Q8J8) Pfam (PF00178) UniProt (by SIFTS) (P97360) | Mus musculus (house mouse) | |
| 4 | M, N, O, P, Q... (C, A, D, E, F...) | water | water | 18.0 | 32 | Chemie (HOH) |
Sequence modifications
A, F, I, L: 329 - 426 (UniProt: E9Q8J8)
| PDB | External Database | Details |
|---|---|---|
| Gly 326 | - | expression tag |
| Ser 327 | - | expression tag |
| Met 328 | - | expression tag |
| Ser 334 | Cys 245 | conflict |
| Tyr 396 | His 307 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 86064.9 | |
| All* | Total formula weight | 86064.9 |
