8E66
ETV6 H396Y variant bound to DNA containing the sequence GGAA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | B, D | GGAA-containing 15 bp DNA | polymer | 15 | 4692.1 | 2 | synthetic construct | ||
| 2 | C, E | Complementary 15 bp strand | polymer | 15 | 4486.9 | 2 | synthetic construct | ||
| 3 | A, F | Transcription factor ETV6 | polymer | 100 | 12180.0 | 2 | UniProt (E9Q8J8) Pfam (PF00178) UniProt (by SIFTS) (P97360) In PDB | Mus musculus (house mouse) | |
| 4 | D | CACODYLATE ION | non-polymer | 137.0 | 1 | Chemie (CAC) | |||
| 5 | water | water | 18.0 | 105 | Chemie (HOH) |
Sequence modifications
A, F: 329 - 425 (UniProt: E9Q8J8)
| PDB | External Database | Details |
|---|---|---|
| Gly 326 | - | expression tag |
| Ser 327 | - | expression tag |
| Met 328 | - | expression tag |
| Ser 334 | Cys 245 | conflict |
| Tyr 396 | His 307 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 42718.0 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 137.0 | |
| All* | Total formula weight | 42855.0 |
