8E5B
Human L-type voltage-gated calcium channel Cav1.3 in the presence of Amiodarone and Sofosbuvir at 3.3 Angstrom resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Voltage-dependent L-type calcium channel subunit alpha-1D | polymer | 2161 | 245417.7 | 1 | UniProt (Q01668) Pfam (PF00520) Pfam (PF08016) Pfam (PF16905) Pfam (PF08763) Pfam (PF16885) In PDB | Homo sapiens (human) | Calcium channel,L type,alpha-1 polypeptide,isoform 2,Voltage-gated calcium channel subunit alpha Cav1.3 |
| 2 | D | Voltage-dependent calcium channel subunit alpha-2/delta-1 | polymer | 1103 | 124692.5 | 1 | UniProt (P54289) Pfam (PF08399) Pfam (PF00092) Pfam (PF08473) In PDB | Homo sapiens (human) | Voltage-gated calcium channel subunit alpha-2/delta-1 |
| 3 | C | Voltage-dependent L-type calcium channel subunit beta-3 | polymer | 484 | 54607.9 | 1 | UniProt (P54284) Pfam (PF00625) Pfam (PF12052) In PDB | Homo sapiens (human) | CAB3,Calcium channel voltage-dependent subunit beta 3 |
| 4 | B | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 627.6 | 1 | In PDB BIRD (PRD_900017) GlyTouCan (G47362BJ) | |||
| 5 | E, G, H | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 3 | In PDB GlyTouCan (G42666HT) | |||
| 6 | F | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 830.8 | 1 | In PDB GlyTouCan (G01361SX) | |||
| 7 | A | (2-butyl-1-benzofuran-3-yl){4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl}methanone | non-polymer | 645.3 | 1 | Chemie (BBI) | |||
| 8 | A | Sofosbuvir | non-polymer | 529.5 | 1 | Chemie (WG6) | |||
| 9 | A, D | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 10 | D | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 424718.1 | |
| Branched | Number of molecules | 5 |
| Total formula weight | 2731.6 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1476.1 | |
| All* | Total formula weight | 428925.8 |
