8E2L
Structure of Lates calcarifer Twinkle helicase with ATP and DNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, D, E, F... (C, A, B, D, E...) | Twinkle mtDNA helicase | polymer | 542 | 61298.2 | 6 | UniProt (A0A4W6C5C5) Pfam (PF13481) | Lates calcarifer (barramundi perch) | |
| 2 | B (M) | DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3') | polymer | 15 | 4517.9 | 1 | synthetic construct | ||
| 3 | H, J, L, N, P (C, B, D, E, F) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 5 | Chemie (ATP) | |||
| 4 | I, K, M, O, Q (C, B, D, E, F) | MAGNESIUM ION | non-polymer | 24.3 | 5 | Chemie (MG) |
Sequence modifications
C, A, B, D, E, F: 1 - 517 (UniProt: A0A4W6C5C5)
C, A, B, D, E, F: 518 - 542 (PDB: 8E2L)
| PDB | External Database | Details |
|---|---|---|
| Gln 325 | Glu 452 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 7 |
| Total formula weight | 372306.9 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 2657.4 | |
| All* | Total formula weight | 374964.3 |
