8DYO
Cryo-EM structure of Importin-4 bound to RanGTP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Importin-4 | polymer | 1081 | 118832.1 | 1 | UniProt (Q8TEX9) Pfam (PF03810) Pfam (PF25780) Pfam (PF25574) Pfam (PF13513) | Homo sapiens (human) | Imp4,Importin-4b,Imp4b,Ran-binding protein 4,RanBP4 |
| 2 | B (B) | GTP-binding nuclear protein GSP1/CNR1 | polymer | 219 | 24825.4 | 1 | UniProt (P32835) Pfam (PF00071) | Saccharomyces cerevisiae (baker's yeast) | Chromosome stability protein 17,GTPase Ran homolog,Genetic suppressor of PRP20-1 |
| 3 | C (B) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) PubChem (888) | |||
| 4 | D (B) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 1 | Chemie (GTP) PubChem (135600366) PubChem (135749822) PubChem (136664747) PubChem (136803486) PubChem (164715984) PubChem (135398633) PubChem (135400627) PubChem (135487750) PubChem (135544356) PubChem (135547949) PubChem (136005188) PubChem (136073923) PubChem (136088935) PubChem (136240914) PubChem (136772743) PubChem (136772744) PubChem (136803487) PubChem (137286749) PubChem (171699466) |
Sequence modifications
B: 1 - 219 (UniProt: P32835)
| PDB | External Database | Details |
|---|---|---|
| Leu 71 | Gln 71 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 143657.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 547.5 | |
| All* | Total formula weight | 144204.9 |
