8DYO
Cryo-EM structure of Importin-4 bound to RanGTP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Importin-4 | polymer | 1081 | 118832.1 | 1 | UniProt (Q8TEX9) Pfam (PF03810) Pfam (PF13513) In PDB | Homo sapiens (human) | Imp4,Importin-4b,Imp4b,Ran-binding protein 4,RanBP4 |
| 2 | B | GTP-binding nuclear protein GSP1/CNR1 | polymer | 219 | 24825.4 | 1 | UniProt (P32835) Pfam (PF00071) In PDB | Saccharomyces cerevisiae (baker's yeast) | Chromosome stability protein 17,GTPase Ran homolog,Genetic suppressor of PRP20-1 |
| 3 | B | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | B | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 1 | Chemie (GTP) |
Sequence modifications
B: 1 - 219 (UniProt: P32835)
| PDB | External Database | Details |
|---|---|---|
| Leu 71 | Gln 71 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 143657.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 547.5 | |
| All* | Total formula weight | 144204.9 |
