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8DW3

Cryo-EM structure of SARS-CoV-2 RBD in complex with anti-SARS-CoV-2 DARPin,SR16m, and two antibody Fabs, S309 and CR3022

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Anti-SARS-CoV-2 DARPin SR16mpolymer16116793.01Homo sapiens (Human)
2B
(B)
Spike protein S1polymer19722100.81UniProt (P0DTC2)
Pfam (PF09408)
Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2)
3C
(C)
Antibody S309 light chainpolymer21423204.71Homo sapiens (Human)
4D
(D)
antibody S309 heavy chainpolymer23024573.51Homo sapiens (Human)
5E
(H)
antibody CR3022 heavy chainpolymer22123382.41Homo sapiens (Human)
6F
(L)
antibody CR3022 light chainpolymer22024289.91Homo sapiens (Human)
7G
(E)
beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched586.51In PDB
GlyTouCan (G15407YE)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight134344.2
BranchedNumber of molecules1
Total formula weight586.5
All*Total formula weight134930.7
*Water molecules are not included.

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PDB entries from 2025-06-11

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