8DT4
X-ray structure of human acetylcholinesterase ternary complex with paraoxon and oxime MMB4 (POX-hAChE-MMB4)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Acetylcholinesterase | polymer | 550 | 60288.0 | 2 | UniProt (P22303) Pfam (PF00135) In PDB | Homo sapiens (human) | AChE |
| 2 | A, B | DIETHYL PHOSPHONATE | non-polymer | 138.1 | 2 | Chemie (DEP) | |||
| 3 | A, B | 1,1'-methylenebis{4-[(E)-(hydroxyimino)methyl]pyridin-1-ium} | non-polymer | 258.3 | 2 | Chemie (3VI) | |||
| 4 | A, B | GLYCEROL | non-polymer | 92.1 | 6 | Chemie (GOL) | |||
| 5 | water | water | 18.0 | 155 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 547 (UniProt: P22303)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Pro -1 | - | expression tag |
| Leu 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 120576.0 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1345.3 | |
| All* | Total formula weight | 121921.3 |
