8DS1
Structure of SARS-CoV-2 Mpro in complex with nsp12-nsp13 (C12) cut site sequence
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | 3C-like proteinase nsp5 | polymer | 306 | 33882.7 | 12 | UniProt (P0DTD1) Pfam (PF05409) | Severe acute respiratory syndrome coronavirus 2 | 3CL-PRO,3CLp,Main protease,Mpro,Non-structural protein 5,nsp5,SARS coronavirus main proteinase |
| 2 | M, O, Q, T, U (A, F, G, K, L) | SODIUM ION | non-polymer | 23.0 | 5 | Chemie (NA) | |||
| 3 | N, P, R, S, V (A, F, G, I, L) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 5 | Chemie (PEG) | |||
| 4 | AA, BA, CA, DA, EA... (E, F, G, H, I...) | water | water | 18.0 | 286 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H, I, J, K, L: 1 - 300 (UniProt: P0DTD1)
| PDB | External Database | Details |
|---|---|---|
| Pro 301 | - | expression tag |
| His 302 | - | expression tag |
| Thr 303 | - | expression tag |
| Val 304 | - | expression tag |
| Leu 305 | - | expression tag |
| Gln 306 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 406591.9 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 645.5 | |
| All* | Total formula weight | 407237.5 |
