8DPB

MeaB in complex with the cobalamin-binding domain of its target mutase with GMPPCP bound

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Methylmalonyl-CoA mutase accessory protein	polymer	329	34492.4	2	UniProt (C5AP93) Pfam (PF03308)	Methylorubrum extorquens AM1
2	C, D (C, D)	Methylmalonyl-CoA mutase, alpha subunit	polymer	191	20232.9	2	UniProt (C5AV67) Pfam (PF02310)	Methylorubrum extorquens AM1
3	E, I (A, B)	PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER	non-polymer		521.2	2	Chemie (GCP)
4	F, J (A, B)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
5	G, H (A)	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
6	K, L, M, N (A, B, C, D)	water	water		18.0	67	Chemie (HOH)

Sequence modifications

C, D: 545 - 712 (UniProt: C5AV67)

PDB	External Database	Details
Met 524	-	initiating methionine
Gly 525	-	expression tag
Ser 526	-	expression tag
Ser 527	-	expression tag
His 528	-	expression tag
His 529	-	expression tag
His 530	-	expression tag
His 531	-	expression tag
His 532	-	expression tag
His 533	-	expression tag
Ser 534	-	expression tag
Ser 535	-	expression tag
Gly 536	-	expression tag
Leu 537	-	expression tag
Val 538	-	expression tag
Pro 539	-	expression tag
Arg 540	-	expression tag
Gly 541	-	expression tag
Ser 542	-	expression tag
His 543	-	expression tag
Met 544	-	expression tag
Leu 713	-	expression tag
Glu 714	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	109450.6
Non-Polymers*	Number of molecules	6
	Total formula weight	1275.2
All*	Total formula weight	110725.8

*Water molecules are not included.