8DN1

Q108K:K40L:T51C:T53A:R58L:Q38F:Q4F mutant of hCRBPII bound to synthetic fluorophore CM1V at pH 7.2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Retinol-binding protein 2	polymer	133	15548.5	1	UniProt (P50120) Pfam (PF00061) In PDB	Homo sapiens (human)	Cellular retinol-binding protein II,CRBP-II
2	A	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
3	A	(2E)-3-[7-(diethylamino)-2-oxo-2H-1-benzopyran-3-yl]prop-2-enal, bound form	non-polymer		257.3	1	Chemie (RH6)
4		water	water		18.0	157	Chemie (HOH)

Sequence modifications

A: 1 - 133 (UniProt: P50120)

PDB	External Database	Details
Phe 4	Gln 5	engineered mutation
Phe 38	Gln 39	engineered mutation
Leu 40	Lys 41	engineered mutation
Cys 51	Thr 52	engineered mutation
Ala 53	Thr 54	engineered mutation
Leu 58	Arg 59	engineered mutation
Lys 108	Gln 109	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	15548.5
Non-Polymers*	Number of molecules	3
	Total formula weight	441.5
All*	Total formula weight	15990.1

*Water molecules are not included.