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8DL8

Cryo-EM structure of human ferroportin/slc40 bound to Co2+ in nanodisc

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Solute carrier family 40 member 1polymer57763386.61UniProt (Q9NP59)
Pfam (PF06963)
Homo sapiens (human)Ferroportin-1,Iron-regulated transporter 1
2B
(C)
11F9 light-chainpolymer21323493.91Mus musculus (mouse)
3C
(D)
11F9 heavy-chainpolymer23825815.01Mus musculus (mouse)
4D, E
(A)
COBALT (II) IONnon-polymer58.92Chemie (CO)
5F
(D)
waterwater18.01Chemie (HOH)
Sequence modifications
A: 1 - 571 (UniProt: Q9NP59)
PDBExternal DatabaseDetails
Glu 572-expression tag
Asn 573-expression tag
Leu 574-expression tag
Tyr 575-expression tag
Phe 576-expression tag
Gln 577-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight112695.5
Non-Polymers*Number of molecules2
Total formula weight117.9
All*Total formula weight112813.4
*Water molecules are not included.

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PDB entries from 2024-10-30

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